{"id":"W4386543825","doi":"10.1093/ofid/ofad467","title":"Biological and Clinical Implications of the Vascular Endothelial Growth Factor Coreceptor Neuropilin-1 in Human Immunodeficiency Virus","year":2023,"lang":"en","type":"article","venue":"Open Forum Infectious Diseases","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Institute of Allergy and Infectious Diseases; National Institute on Aging; MacroGenics; Agency for Healthcare Research and Quality; Kowa Company; Regeneron Pharmaceuticals; Gilead Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; Amgen; ViiV Healthcare; GlaxoSmithKline; National Heart, Lung, and Blood Institute; Pfizer; National Institute on Drug Abuse; Eli Lilly and Company; National Center for Advancing Translational Sciences; ACT Government; American Heart Association; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Medicine; Neuropilin 1; Angiogenesis; Vascular endothelial growth factor; Myocardial infarction; Clinical trial; Growth factor; Immunology; Stroke (engine); Internal medicine; Bioinformatics; Oncology; VEGF receptors; Receptor; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001374312,0.0001633477,0.0002545366,0.0002086373,0.0001174501,0.0003958528,0.0002390576,0.0003086183,0.0008769392],"category_scores_gemma":[0.0025899,0.00008679032,0.0002052447,0.0002338449,0.0002770944,0.0002115127,0.0001903812,0.000518847,0.00005223966],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003420353,"about_ca_system_score_gemma":0.0002924075,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001208896,"about_ca_topic_score_gemma":0.001141952,"domain_scores_codex":[0.9995844,0.0002500628,0.00001953282,0.00005014107,0.00005043732,0.00004544324],"domain_scores_gemma":[0.9990476,0.0004892799,0.0002361791,0.00003930621,0.00006694748,0.0001207331],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01997185,0.0008366104,0.8418436,0.0004815157,0.000600088,0.001167389,0.0001498377,0.001356202,0.02665075,0.00126841,0.001801495,0.1038722],"study_design_scores_gemma":[0.0005804384,0.00270752,0.9856679,0.00009527597,0.0004099878,0.001353091,0.0001410656,0.002995136,0.00376788,0.0008921745,0.001370804,0.0000186643],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933409,0.004925877,0.0001294437,0.0004825836,0.00002053058,0.00001734231,0.0003086344,0.000004147518,0.0007705698],"genre_scores_gemma":[0.9989585,0.0005163822,0.000136783,0.0001090344,0.00002278396,0.000007980884,0.0001308996,6.604039e-7,0.0001171163],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001374312,"threshold_uncertainty_score":0.007268131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03013329821991607,"score_gpt":0.3300360753604044,"score_spread":0.2999027771404884,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}