{"id":"W4386543825","doi":"10.1093/ofid/ofad467","title":"Biological and Clinical Implications of the Vascular Endothelial Growth Factor Coreceptor Neuropilin-1 in Human Immunodeficiency Virus","year":2023,"lang":"en","type":"article","venue":"Open Forum Infectious Diseases","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Institute of Allergy and Infectious Diseases; National Institute on Aging; MacroGenics; Agency for Healthcare Research and Quality; Kowa Company; Regeneron Pharmaceuticals; Gilead Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; Amgen; ViiV Healthcare; GlaxoSmithKline; National Heart, Lung, and Blood Institute; Pfizer; National Institute on Drug Abuse; Eli Lilly and Company; National Center for Advancing Translational Sciences; ACT Government; American Heart Association; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Medicine; Neuropilin 1; Angiogenesis; Vascular endothelial growth factor; Myocardial infarction; Clinical trial; Growth factor; Immunology; Stroke (engine); Internal medicine; Bioinformatics; Oncology; VEGF receptors; Receptor; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001071515,0.000107235,0.0001640851,0.00003014873,0.0001683305,0.00003006749,0.0003351701,0.0000860257,0.00005194304],"category_scores_gemma":[0.0001999198,0.00007421029,0.0001816285,0.000177944,0.0002098297,0.000005958822,0.0005347251,0.00005464038,0.00000659911],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009452669,"about_ca_system_score_gemma":0.00006126252,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001593728,"about_ca_topic_score_gemma":0.0001401592,"domain_scores_codex":[0.9990712,0.0001217536,0.0002634663,0.0002977326,0.00006240159,0.0001834894],"domain_scores_gemma":[0.999458,0.00004482973,0.00009329351,0.0003045952,0.00004867983,0.00005061054],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00001975937,0.0001705957,0.9125083,0.00000429273,0.00003042342,2.946889e-7,0.000005267366,0.000005551182,0.08493105,0.0007041908,0.0004510055,0.001169268],"study_design_scores_gemma":[0.0005364919,0.0002668257,0.9883007,0.000007789644,0.00001846424,0.000001661674,0.00002031469,0.000005630217,0.006797769,0.0006729411,0.003259774,0.0001116426],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979959,0.0004382715,0.00002038941,0.0001414103,0.0001476386,0.000351057,0.0002977611,0.00001046894,0.0005971721],"genre_scores_gemma":[0.9981794,0.001364446,0.000003229763,0.0002031911,0.000049224,0.00005947132,0.00006026962,0.00001305935,0.00006768975],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07813328,"threshold_uncertainty_score":0.3026207,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03013329821991607,"score_gpt":0.3300360753604044,"score_spread":0.2999027771404884,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}