{"id":"W4386569834","doi":"10.1111/imm.13691","title":"Dysregulation of B lymphocyte development in the <scp>SKG</scp> mouse model of rheumatoid arthritis","year":2023,"lang":"en","type":"article","venue":"Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research; Canada Research Chairs; McGill University","keywords":"Immunology; Bone marrow; B cell; Rheumatoid arthritis; Arthritis; Lymphocyte; Flow cytometry; Population; Spleen; Medicine; Autoantibody; Biology; Antibody","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006094596,0.0002521356,0.0005954711,0.0004790982,0.0001419421,0.000005756299,0.0006398399,0.0005338367,0.00005063875],"category_scores_gemma":[0.0001700117,0.0002087649,0.0001157949,0.0005155024,0.0006709,0.00008830051,0.0002314893,0.0003330497,0.000495958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006323982,"about_ca_system_score_gemma":0.0002421929,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001882215,"about_ca_topic_score_gemma":0.0001210845,"domain_scores_codex":[0.9976877,0.0004009143,0.0009005599,0.0003393415,0.00006833181,0.0006031746],"domain_scores_gemma":[0.9984251,0.000513903,0.0003689556,0.0005691816,0.0001132356,0.000009671729],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005588773,0.0002123565,0.0009063943,0.0000178286,0.0002076903,0.000004224074,0.004446707,0.0004807532,0.9766327,0.003440542,0.0006496838,0.01294522],"study_design_scores_gemma":[0.003113215,0.0001828739,0.004634452,0.00005956649,0.000008137277,0.00007884469,0.001752979,0.0001652792,0.9705638,0.001054495,0.01828662,0.00009977178],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886321,0.009486283,0.0001616523,0.0001147579,0.0004633043,0.0003032548,0.00002718562,0.00009556828,0.0007158943],"genre_scores_gemma":[0.9920186,0.005466867,0.0001548508,0.00006077199,0.000006334648,0.0000788842,0.0002057817,0.00002556056,0.001982349],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01763693,"threshold_uncertainty_score":0.8513187,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01565604109475143,"score_gpt":0.2151259620124094,"score_spread":0.199469920917658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}