{"id":"W4386575306","doi":"10.1016/s2468-1253(23)00205-4","title":"Serum anti-tissue transglutaminase IgA and prediction of duodenal villous atrophy in adults with suspected coeliac disease without IgA deficiency (Bi.A.CeD): a multicentre, prospective cohort study","year":2023,"lang":"en","type":"article","venue":"˜The œLancet. Gastroenterology & hepatology","topic":"Celiac Disease Research and Management","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Hospital Foundation","funders":"Università degli Studi di Salerno","keywords":"Villous atrophy; Tissue transglutaminase; Coeliac disease; Medicine; Gastroenterology; Internal medicine; Immunoglobulin A; Prospective cohort study; Atrophy; Cohort; Duodenum; Biopsy; Pathology; Disease; Immunology; Antibody; Immunoglobulin G; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001331257,0.0008031394,0.0007801399,0.000585204,0.0006812617,0.001464378,0.0009101046,0.001654516,0.001482965],"category_scores_gemma":[0.002272905,0.001093639,0.00125319,0.00122296,0.000478802,0.0007458701,0.0007637787,0.001550896,0.0004130448],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004752791,"about_ca_system_score_gemma":0.0004152156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00896352,"about_ca_topic_score_gemma":0.009750896,"domain_scores_codex":[0.9993881,0.0001739677,0.00006815507,0.0001756845,0.00008157442,0.0001125281],"domain_scores_gemma":[0.9985402,0.0002668511,0.0004148337,0.0002778151,0.000147941,0.0003524333],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001901183,0.0001500342,0.9958659,0.00002258133,0.0003979237,0.0001769521,0.00007576075,0.00003987992,0.0005238376,0.00002457945,0.0001749461,0.0006463517],"study_design_scores_gemma":[0.0002018578,0.0003907202,0.9983389,0.00001129434,0.0002751472,0.0003022817,0.0001241672,0.0001879638,0.0000389959,0.00001812295,0.0001013423,0.000009075974],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989021,0.0004448727,0.0000384136,0.00004839411,0.00001904627,0.00001094948,0.0003702081,0.000003277526,0.0001627142],"genre_scores_gemma":[0.9990432,0.0001920808,0.00007984032,0.00004923409,0.00002790529,0.0000126156,0.0004206401,0.000001833241,0.0001726936],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00896352,"threshold_uncertainty_score":0.01782268,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009577304213111123,"score_gpt":0.2611338468064573,"score_spread":0.2515565425933462,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}