{"id":"W4386594290","doi":"10.1016/j.placenta.2023.07.229","title":"Placenta NAD+ depletion: A mechanism through which maternal obesity may drive placenta and fetal programming","year":2023,"lang":"en","type":"article","venue":"Placenta","topic":"Birth, Development, and Health","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Placenta; Mechanism (biology); Fetal programming; NAD+ kinase; Fetus; Obstetrics; Andrology; Chemistry; Medicine; Biology; Pregnancy; Biochemistry; Genetics; Physics; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004104487,0.0002426226,0.000325126,0.0003580098,0.0004124553,0.001041262,0.0005881027,0.0007123767,0.002350301],"category_scores_gemma":[0.0007890587,0.0002598094,0.0002808762,0.0002378425,0.0006457824,0.0005954607,0.0009710639,0.0009109913,0.0002287973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008662207,"about_ca_system_score_gemma":0.0009120801,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001611996,"about_ca_topic_score_gemma":0.002411506,"domain_scores_codex":[0.9998201,0.0000456152,0.000009466279,0.00004538042,0.00003061627,0.0000489855],"domain_scores_gemma":[0.9995971,0.00008660539,0.0001059396,0.00007057122,0.00004392917,0.00009579151],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003038208,0.0001912928,0.02490279,0.0007073754,0.000173643,0.002737537,0.0007651152,0.0007891906,0.8573937,0.05280828,0.00207458,0.05441836],"study_design_scores_gemma":[0.0003930272,0.002527314,0.1860396,0.000461044,0.0004038908,0.008934878,0.003066738,0.006440865,0.6127091,0.0857029,0.09318904,0.0001315687],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8895282,0.03018768,0.04052922,0.01239131,0.0008576501,0.00009325276,0.0009509056,0.0005331968,0.02492863],"genre_scores_gemma":[0.9842626,0.006210567,0.004506811,0.0008081876,0.0000941261,0.00003941868,0.0001701855,0.00002908337,0.003878997],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002350301,"threshold_uncertainty_score":0.007862568,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02878272788357482,"score_gpt":0.2965147131008787,"score_spread":0.2677319852173039,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}