{"id":"W4386601220","doi":"10.3390/math11183860","title":"Sensor Selection and State Estimation of Continuous mAb Production Processes","year":2023,"lang":"en","type":"article","venue":"Mathematics","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biomanufacturing; Estimation; Selection (genetic algorithm); Production (economics); Computer science; Mean squared error; Process (computing); State (computer science); Mathematical optimization; Mathematics; Statistics; Algorithm; Artificial intelligence; Engineering; Biotechnology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001054199,0.0006496502,0.00063618,0.0004194681,0.0003038258,0.0008254404,0.0005320086,0.0007092755,0.0006474917],"category_scores_gemma":[0.002956876,0.000260882,0.0005111225,0.0002827643,0.0004989737,0.0006187724,0.0006751856,0.0007227669,0.0001419665],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004175313,"about_ca_system_score_gemma":0.0004879746,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002813105,"about_ca_topic_score_gemma":0.001394525,"domain_scores_codex":[0.9994248,0.0001917793,0.00003486178,0.0001523933,0.0001476281,0.00004856942],"domain_scores_gemma":[0.9988575,0.0007632333,0.0001577181,0.00005520455,0.0001491975,0.00001713779],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0001644555,0.0000707331,0.002621716,0.0001752572,0.00003718883,0.0001293223,0.0001472595,0.8970304,0.02986598,0.005286856,0.0002297291,0.06424117],"study_design_scores_gemma":[0.000003675542,0.0000382101,0.0005662913,0.000004638246,0.000005014107,0.00001119692,0.00001035348,0.9930997,0.005298547,0.0007949218,0.0001608794,0.000006632661],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.0509437,0.0001936983,0.9475108,0.0000890802,0.00001534974,0.00002748193,0.00003283045,0.0001819874,0.001005018],"genre_scores_gemma":[0.9472278,0.0001684206,0.05186523,0.00001944843,0.00001084872,0.00005408837,0.00005784816,0.00001315248,0.0005830947],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002813105,"threshold_uncertainty_score":0.005593479,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009487094713338471,"score_gpt":0.2613071766657714,"score_spread":0.2518200819524329,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}