{"id":"W4386608057","doi":"10.1016/j.immuni.2023.08.009","title":"Tertiary lymphoid structures and B cells: An intratumoral immunity cycle","year":2023,"lang":"en","type":"review","venue":"Immunity","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":284,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Sorbonne Université; Institute of Cancer Research; Institut National Du Cancer; Ligue Contre le Cancer; Institut National de la Santé et de la Recherche Médicale; Fondation ARC pour la Recherche sur le Cancer; Agence Nationale de la Recherche; Université de Paris; Association pour la Recherche sur le Cancer","keywords":"Biology; Follicular dendritic cells; Immunity; Antibody; Immunology; Context (archaeology); Immune system; Antigen; Affinity maturation; Antigen presentation; Lymphatic system; Cancer research; Antigen-presenting cell; T cell","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006316347,0.0005761177,0.001602432,0.0002751498,0.0003225578,0.0001028078,0.0004255236,0.000471241,0.0002069339],"category_scores_gemma":[0.00005324204,0.0004466393,0.0004332059,0.0004710221,0.0003606904,0.0001497065,0.0002449648,0.001073078,0.00004350632],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002365438,"about_ca_system_score_gemma":0.0005679902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003218321,"about_ca_topic_score_gemma":0.0001239467,"domain_scores_codex":[0.9976252,0.000593316,0.0007000114,0.0003973468,0.0002544055,0.0004296798],"domain_scores_gemma":[0.998013,0.0001826422,0.0002921624,0.001245928,0.00006223778,0.0002040883],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002122914,0.0001316764,0.0000349278,0.01059854,0.0007132977,0.0000714981,0.0002581157,6.922928e-8,0.0002900792,0.00001363863,0.0005016768,0.9871742],"study_design_scores_gemma":[0.002002983,0.0005920582,0.003879644,0.01161403,0.002232395,0.001286644,0.0003890751,0.00001108984,0.0002572424,0.0003346378,0.9763547,0.001045569],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01428135,0.9834465,0.000001518827,0.00002472242,0.0006321764,0.0008415388,0.000156326,0.0002459811,0.0003698846],"genre_scores_gemma":[0.001135033,0.9971005,0.0001054234,0.0001854119,0.0002506305,0.00005783041,0.0006282012,0.000125004,0.0004119273],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9861286,"threshold_uncertainty_score":0.9997985,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0494682716950751,"score_gpt":0.3523987208875468,"score_spread":0.3029304491924716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}