{"id":"W4386614420","doi":"10.1002/mrm.29875","title":"Current methods for hyperpolarized [<scp>1‐<sup>13</sup>C</scp>]pyruvate <scp>MRI</scp> human studies","year":2024,"lang":"en","type":"review","venue":"Magnetic Resonance in Medicine","topic":"Advanced NMR Techniques and Applications","field":"Chemistry","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"National Institute of Biomedical Imaging and Bioengineering; National Institutes of Health; National Cancer Institute; Chang Gung Medical Foundation; Eidgenössische Technische Hochschule Zürich; Albert-Ludwigs-Universität Freiburg; University of Texas MD Anderson Cancer Center; Memorial Sloan-Kettering Cancer Center; Institute for Bioengineering of Catalonia; University of Oxford; Danmarks Tekniske Universitet; Aarhus Universitet; Technische Universität München","keywords":"Computer science; Glycolysis; Key (lock); Medicine; Nuclear magnetic resonance; Nuclear medicine; Chemistry; Medical physics; Physics; Metabolism; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.001575757,0.001418114,0.004349631,0.0004953474,0.0002884121,0.00006236513,0.001388397,0.0007102301,0.00008198753],"category_scores_gemma":[0.003333627,0.001067132,0.0007009454,0.001286124,0.0007837932,0.0000854704,0.0005268345,0.002133297,0.00005757089],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004402033,"about_ca_system_score_gemma":0.0002003113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003199626,"about_ca_topic_score_gemma":0.00001044134,"domain_scores_codex":[0.9936978,0.0002172625,0.0024242,0.00186659,0.0005994648,0.00119466],"domain_scores_gemma":[0.9928082,0.004205966,0.0007387917,0.001705815,0.0002684085,0.0002728427],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000001627421,0.0001095249,0.000006695656,0.03073184,0.00008421913,0.00002273037,0.0005422526,0.000002867023,0.000153495,0.001569051,0.04012397,0.9266517],"study_design_scores_gemma":[0.0008502704,0.0001960579,0.000002581917,0.03870207,0.00161274,0.0000331114,0.0004957913,0.0004426547,0.0000708493,0.01184055,0.9455153,0.0002380227],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003994659,0.9894797,0.003622028,0.000159772,0.0002140732,0.002364711,0.0002440737,0.0004992487,0.003376509],"genre_scores_gemma":[0.000002126136,0.9379099,0.03621015,0.00009736905,0.001481769,0.008043119,0.0004375583,0.0002910569,0.01552697],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9264137,"threshold_uncertainty_score":0.9998569,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09757651714433611,"score_gpt":0.4694260164197936,"score_spread":0.3718494992754575,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}