{"id":"W4386617915","doi":"10.20944/preprints202309.0591.v1","title":"Cross-Recognition of the ssgBp Promoter, Which Controls the Expression of the Sporulation–Specific Cell Division Gene ssgB, by Nine SigB Homologues in Streptomyces coelicolor A3(2)","year":2023,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Slovenská Akadémia Vied; McMaster University","keywords":"Streptomyces coelicolor; Promoter; Luciferase; Mutant; Sigma factor; Plasmid; Reporter gene; Bacillus subtilis; Biology; Gene; Streptomyces; Molecular biology; Gene expression; Genetics; Bacteria; Transfection","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001820419,0.0005761846,0.0002797983,0.0002776784,0.000152327,0.0003127133,0.0002199043,0.0002632611,0.0008130857],"category_scores_gemma":[0.0001355799,0.0002428209,0.0003937889,0.0002104297,0.0003272466,0.0001277737,0.0004551161,0.0006880688,0.0004580849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000460228,"about_ca_system_score_gemma":0.0002765307,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009707392,"about_ca_topic_score_gemma":0.00183451,"domain_scores_codex":[0.9997174,0.00006112,0.00003572221,0.00006601039,0.00007361175,0.00004604612],"domain_scores_gemma":[0.9997798,0.0000327058,0.00006874996,0.00002554007,0.00001478406,0.00007843012],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003553596,0.00001406248,0.0001259912,0.000009098208,0.000001465897,0.00001393652,0.000006283804,0.0000163546,0.9994874,0.00001682227,0.000004155298,0.0002689507],"study_design_scores_gemma":[0.00001631347,0.0002955711,0.007486616,0.000008240831,0.00001398504,0.000268324,0.00003799624,0.0007607465,0.9900517,0.00002404953,0.001030631,0.000005900577],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995322,0.0004123459,0.003463715,0.00003701278,0.00001584864,0.00002383548,0.0002485656,0.00003971274,0.0004368625],"genre_scores_gemma":[0.992649,0.0002383961,0.003744498,0.00005217609,0.000006531588,0.00003849242,0.001308099,0.00003492436,0.001927936],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009707392,"threshold_uncertainty_score":0.003339171,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08874322633477555,"score_gpt":0.3220222486508601,"score_spread":0.2332790223160845,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}