{"id":"W4386623583","doi":"10.1002/cam4.6520","title":"Update on immune‐based therapy strategies targeting cancer stem cells","year":2023,"lang":"en","type":"review","venue":"Cancer Medicine","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research; University of Calgary","funders":"","keywords":"Cancer stem cell; CD44; Cancer research; Chimeric antigen receptor; Oncolytic virus; Immunotherapy; Immune checkpoint; Cancer; Medicine; Epithelial cell adhesion molecule; Immune system; Immunology; Biology; Antigen; Cell; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006929091,0.001073887,0.004434372,0.0005575886,0.0001512666,0.00004224039,0.0004190976,0.0004144282,0.003657034],"category_scores_gemma":[0.00002033775,0.0006875761,0.0007906242,0.001235385,0.0003555393,0.0000701741,0.00005752403,0.001150214,0.0002462941],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008343718,"about_ca_system_score_gemma":0.0034034,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001553417,"about_ca_topic_score_gemma":0.00007563757,"domain_scores_codex":[0.9955387,0.0001856013,0.001417343,0.001078583,0.0009225665,0.0008572194],"domain_scores_gemma":[0.9972246,0.0002788875,0.0008829002,0.0009678893,0.0002316444,0.0004140359],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000152947,0.0000603224,0.00000149087,0.02642839,0.0008861141,0.000151013,0.000122695,0.00003970101,0.0001481405,0.00006463136,0.04452046,0.9274241],"study_design_scores_gemma":[0.00226933,0.0004059894,0.000002165971,0.07305122,0.00240949,0.000005727068,0.0002513341,0.0000110135,0.0004465237,0.000008810917,0.9205947,0.0005436805],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000220795,0.9895275,0.00003213541,0.001666587,0.004691971,0.002128141,0.0003722973,0.0003018017,0.001257552],"genre_scores_gemma":[0.00003216174,0.9870639,0.0000380743,0.001852862,0.004328724,0.001472383,0.0003425429,0.0003538468,0.004515474],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9268804,"threshold_uncertainty_score":0.9995576,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1678532784232037,"score_gpt":0.4275101878155313,"score_spread":0.2596569093923276,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}