{"id":"W4386640941","doi":"10.1016/j.jtho.2023.07.017","title":"International Association for the Study of Lung Cancer Study of Reproducibility in Assessment of Pathologic Response in Resected Lung Cancers After Neoadjuvant Therapy","year":2023,"lang":"en","type":"article","venue":"Journal of Thoracic Oncology","topic":"Lung Cancer Diagnosis and Treatment","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; University Health Network","funders":"EMD Serono; Genentech; Eisai; Ministerio de Ciencia e Innovación; Daiichi-Sankyo; Parker Institute for Cancer Immunotherapy; Regeneron Pharmaceuticals; F. Hoffmann-La Roche; Yale University; Daiichi Sankyo Europe; Sanofi; Arrowhead Pharmaceuticals; GlaxoSmithKline; Amgen; Pfizer; Society for Immunotherapy of Cancer; AstraZeneca; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Medicine; Lung cancer; Neoadjuvant therapy; Adenocarcinoma; Concordance; Lung; Confidence interval; Internal medicine; H&E stain; Cancer; Oncology; Radiology; Pathology; Breast cancer; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.06475246,0.0007147204,0.001619518,0.002399925,0.001298574,0.002815068,0.001738183,0.001942644,0.0008005896],"category_scores_gemma":[0.07897389,0.0008054924,0.002625407,0.003182132,0.001737826,0.001386248,0.002104255,0.001664462,0.0002929969],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001056424,"about_ca_system_score_gemma":0.001636192,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00388008,"about_ca_topic_score_gemma":0.004133477,"domain_scores_codex":[0.950153,0.03484769,0.005586763,0.003001954,0.005339638,0.001070974],"domain_scores_gemma":[0.8599002,0.08125395,0.02507179,0.02079635,0.01034189,0.00263587],"domain_codex":null,"domain_gemma":"reproducibility","domain_candidate":"reproducibility","domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002401451,0.00005860604,0.9925701,0.00006195654,0.002127507,0.00002933077,0.0002592141,0.0001626516,0.0001718103,0.0001214731,0.0002218922,0.001813959],"study_design_scores_gemma":[0.0002052305,0.0005015534,0.9957597,0.00004306118,0.0009859152,0.0001298475,0.000220811,0.0008685405,0.0002013887,0.0001476014,0.0009159187,0.00002054352],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9775505,0.009347646,0.004234646,0.0004999025,0.0006261619,0.0004693881,0.001975276,0.00006585193,0.005230719],"genre_scores_gemma":[0.9971137,0.0003413859,0.0009303392,0.00009471674,0.0001250573,0.0002447337,0.0007558895,0.00004220587,0.0003520013],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9352475,"threshold_uncertainty_score":0.3424478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04820853676257156,"score_gpt":0.5102898653406654,"score_spread":0.4620813285780939,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}