{"id":"W4386651916","doi":"10.21203/rs.3.rs-1348366/v1","title":"Whole-Exome Sequencing Identified Mutational Profiles of Urothelial Carcinoma post Kidney Transplantation","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"Kaohsiung Medical University Chung-Ho Memorial Hospital; Universität zu Köln; Kaohsiung Medical University","keywords":"Exome sequencing; Transplantation; Kidney transplantation; Exome; Biology; Single-nucleotide polymorphism; GNAQ; Gene; Cancer research; Bioinformatics; Genetics; Medicine; Mutation; Internal medicine; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002025295,0.0001729036,0.0003011976,0.0007203292,0.0003741531,0.0005140513,0.0002097005,0.0004069246,0.001372986],"category_scores_gemma":[0.0007928421,0.000104897,0.0003978342,0.0008497593,0.0001306541,0.0001778621,0.0003563618,0.0002637367,0.0001987777],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002437378,"about_ca_system_score_gemma":0.0002149031,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001756326,"about_ca_topic_score_gemma":0.001824758,"domain_scores_codex":[0.9997786,0.0000201772,0.00002870785,0.00008312186,0.00004569721,0.000043719],"domain_scores_gemma":[0.9996922,0.00008684663,0.0000855289,0.00002718578,0.00006439298,0.00004384624],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001182671,0.00008238719,0.8928891,0.000158693,0.0002315313,0.004785744,0.0004138388,0.0008465901,0.07946195,0.0001481779,0.0009181082,0.01888118],"study_design_scores_gemma":[0.00001529939,0.00009511905,0.9850097,0.00002762315,0.0001370807,0.003673556,0.0002280695,0.001536399,0.007925939,0.0001608074,0.00117757,0.00001280853],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998278,0.000326091,0.0002498925,0.00003567506,0.000004134753,0.000005372878,0.0009076183,0.00001009564,0.0001830545],"genre_scores_gemma":[0.997667,0.0001328476,0.0002495163,0.00004581428,0.00000375264,0.000008744725,0.001626434,0.000006001645,0.0002599247],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001756326,"threshold_uncertainty_score":0.004593134,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08415819564510779,"score_gpt":0.3775642592226353,"score_spread":0.2934060635775275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}