{"id":"W4386687450","doi":"10.1093/noajnl/vdad106","title":"Phase II trial of concurrent sunitinib, temozolomide, and radiotherapy with adjuvant temozolomide for newly diagnosed MGMT unmethylated glioblastoma","year":2023,"lang":"en","type":"article","venue":"Neuro-Oncology Advances","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Canadian Cancer Society Research Institute; Pfizer","keywords":"Temozolomide; Glioblastoma; Medicine; Sunitinib; Oncology; Adjuvant; Internal medicine; Radiation therapy; Cancer research; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00143245,0.001413123,0.002392929,0.000443782,0.000361412,0.0007844428,0.0008491639,0.0009125615,0.002432103],"category_scores_gemma":[0.0006558432,0.0005658244,0.001064545,0.0003570585,0.0009111171,0.000713912,0.0003654644,0.002511707,0.0005351918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001008722,"about_ca_system_score_gemma":0.001800769,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001234918,"about_ca_topic_score_gemma":0.002703253,"domain_scores_codex":[0.9995607,0.0002088594,0.00002675568,0.00008000595,0.00003372276,0.00008996168],"domain_scores_gemma":[0.9992549,0.00008236421,0.0001395648,0.00005563902,0.00004582633,0.0004216366],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8632429,0.05515992,0.006156147,0.0003787001,0.001064651,0.0002017736,0.0001589154,0.002370991,0.02661168,0.0001710669,0.001620136,0.04286316],"study_design_scores_gemma":[0.4995342,0.4860844,0.00741358,0.00002051548,0.0003360052,0.0001883388,0.00004315437,0.001500292,0.003636821,0.0001309227,0.001090158,0.00002171542],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955322,0.001193764,0.0003995259,0.0001884703,0.0001090201,0.001611354,0.0003607628,0.000044565,0.0005603647],"genre_scores_gemma":[0.9935589,0.0007538041,0.00111281,0.0003287158,0.0001500362,0.001731857,0.001055009,0.00001424836,0.001294607],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002432103,"threshold_uncertainty_score":0.008136213,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02338004956320333,"score_gpt":0.3495038083548198,"score_spread":0.3261237587916164,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}