{"id":"W4386687450","doi":"10.1093/noajnl/vdad106","title":"Phase II trial of concurrent sunitinib, temozolomide, and radiotherapy with adjuvant temozolomide for newly diagnosed MGMT unmethylated glioblastoma","year":2023,"lang":"en","type":"article","venue":"Neuro-Oncology Advances","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Canadian Cancer Society Research Institute; Pfizer","keywords":"Temozolomide; Glioblastoma; Medicine; Sunitinib; Oncology; Adjuvant; Internal medicine; Radiation therapy; Cancer research; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002891885,0.0003638003,0.001141324,0.000345007,0.0002097665,0.00001170722,0.0001198074,0.000178052,0.0000383841],"category_scores_gemma":[0.0004752508,0.0002678405,0.0001587364,0.0005630543,0.0004405776,0.0001430513,0.00005139726,0.0002079688,0.000005036636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008139152,"about_ca_system_score_gemma":0.0002167781,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001400744,"about_ca_topic_score_gemma":0.00008846571,"domain_scores_codex":[0.9978431,0.0001719991,0.0006187446,0.0006067232,0.0002553035,0.0005041142],"domain_scores_gemma":[0.9961832,0.00267873,0.0004113519,0.0003121474,0.0001756828,0.0002389408],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.1783255,0.01095912,0.005387268,0.0003065011,0.0007990638,0.001954039,0.000863716,0.0001637756,0.1984584,0.0004317343,0.005187475,0.5971635],"study_design_scores_gemma":[0.5198507,0.1855729,0.0015486,0.0001759831,0.0006369861,0.0002348995,0.0004463118,0.0007151235,0.1197593,0.0001579962,0.1705078,0.0003933735],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891943,0.00365808,0.00007666327,0.002768569,0.000774875,0.003106617,0.0001318754,0.0001824165,0.0001065833],"genre_scores_gemma":[0.9911822,0.005731909,0.001033713,0.0005870928,0.0002637339,0.001001324,0.00009042962,0.00006534589,0.00004426308],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5967701,"threshold_uncertainty_score":0.9999774,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02338004956320333,"score_gpt":0.3495038083548198,"score_spread":0.3261237587916164,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}