{"id":"W4386691645","doi":"10.21203/rs.3.rs-3260170/v1","title":"A molecular atlas of brain neurovascular interactions reveals a spatiotemporal requirement of TGFβ signaling in brain angiogenesis","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Heart Institute; Polytechnique Montréal; Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"","keywords":"Neurovascular bundle; Atlas (anatomy); Angiogenesis; Neuroscience; Biology; Anatomy; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001124308,0.0004243786,0.0002276165,0.001424144,0.0003433805,0.0008473183,0.0002471306,0.0005415734,0.006090515],"category_scores_gemma":[0.000104883,0.0002474718,0.0003321416,0.0009319502,0.0003186721,0.0006662875,0.0003365988,0.001041767,0.001513553],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002918858,"about_ca_system_score_gemma":0.0003581637,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001267965,"about_ca_topic_score_gemma":0.00164856,"domain_scores_codex":[0.9999477,0.000005266933,0.000002337243,0.00001219558,0.0000158757,0.00001657629],"domain_scores_gemma":[0.9999318,0.00001461385,0.0000146844,0.00001299178,0.00001011926,0.00001581962],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003744592,0.00003893542,0.001898736,0.0004152537,0.00006620026,0.000948194,0.00016438,0.005798294,0.8873541,0.0445461,0.007683379,0.05071191],"study_design_scores_gemma":[0.0001134993,0.0002635751,0.07128281,0.0002108416,0.0002320393,0.01012451,0.0005397865,0.05006921,0.5792243,0.05856856,0.2292547,0.0001160281],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5556285,0.01857278,0.3350295,0.003313897,0.0008108359,0.0001263651,0.01114574,0.006127671,0.0692447],"genre_scores_gemma":[0.7921539,0.01087198,0.1450896,0.0002971675,0.0001962178,0.0001289432,0.002969963,0.0008623956,0.04742983],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006090515,"threshold_uncertainty_score":0.02037483,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08946388590370437,"score_gpt":0.4128408322947705,"score_spread":0.3233769463910662,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}