{"id":"W4386698734","doi":"10.1101/gad.350597.123","title":"Uncovering a mammalian neural-specific poly(A) binding protein with unique properties","year":2023,"lang":"en","type":"article","venue":"Genes & Development","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Toronto; Jewish General Hospital","funders":"National Human Genome Research Institute; Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Cancer Institute; National Institutes of Health; Jewish General Hospital","keywords":"Biology; EIF4G; Poly(A)-binding protein; Cell biology; RNA-binding protein; EIF4E; Polyadenylation; Translation (biology); P-bodies; Messenger RNA; RNA; EIF4EBP1; Molecular biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007591996,0.0002158975,0.0001688549,0.0001559624,0.0001353313,0.0002344354,0.0001958785,0.0002979366,0.0005059439],"category_scores_gemma":[0.000109783,0.00008576061,0.000201558,0.0001825689,0.0001819579,0.0002164999,0.000194688,0.0003435223,0.0003885823],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001588219,"about_ca_system_score_gemma":0.0001301278,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002063613,"about_ca_topic_score_gemma":0.0002843942,"domain_scores_codex":[0.9999564,0.000003339238,0.000003070506,0.00001871075,0.00001154669,0.000006928261],"domain_scores_gemma":[0.999934,0.000007168719,0.00002320447,0.000007591864,0.000008614416,0.00001948346],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003206479,0.000007385711,0.0009510201,0.00005556893,0.000006844034,0.0001952064,0.000007424327,0.00005635811,0.9950936,0.0002253837,0.0000561761,0.003312998],"study_design_scores_gemma":[0.00001443307,0.0003188043,0.06771863,0.00001842823,0.00009713853,0.006042587,0.00006434404,0.005739439,0.8907833,0.0007274709,0.0284527,0.0000227217],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9720218,0.00606659,0.01897086,0.0002500235,0.00007375114,0.00002778405,0.000639405,0.0001357198,0.001814156],"genre_scores_gemma":[0.9648805,0.004836974,0.02334115,0.0002422909,0.00007439545,0.00003607544,0.002421667,0.00003954822,0.004127423],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005059439,"threshold_uncertainty_score":0.001692593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02438937612932688,"score_gpt":0.2389434254120175,"score_spread":0.2145540492826906,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}