{"id":"W4386700150","doi":"10.1016/j.jchf.2023.06.036","title":"Efficacy and Safety of Empagliflozin According to Background Diuretic Use in HFrEF","year":2023,"lang":"en","type":"article","venue":"JACC Heart Failure","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Toronto; St. Michael's Hospital","funders":"Boehringer Ingelheim","keywords":"Empagliflozin; Medicine; Diuretic; Heart failure; Ejection fraction; Internal medicine; Furosemide; Placebo; Population; Cardiology; Randomized controlled trial; Diabetes mellitus; Endocrinology; Type 2 diabetes","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003537666,0.0005069142,0.002053761,0.0003339082,0.000223887,0.0006955774,0.0003796175,0.001084919,0.001060369],"category_scores_gemma":[0.004523864,0.0003556023,0.002259786,0.0004020755,0.0003567919,0.0005817608,0.0004168421,0.001617617,0.0002067571],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000312863,"about_ca_system_score_gemma":0.0003043509,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007246165,"about_ca_topic_score_gemma":0.001207787,"domain_scores_codex":[0.9979435,0.001158957,0.0001789322,0.0003225975,0.0002140266,0.000182051],"domain_scores_gemma":[0.9979608,0.001030328,0.000464766,0.0001912753,0.0001066926,0.000246038],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.8321966,0.002321874,0.07617246,0.0008695362,0.007237123,0.0000744774,0.00009228317,0.001327722,0.003574561,0.000265925,0.001076847,0.07479067],"study_design_scores_gemma":[0.3672331,0.07185517,0.5335748,0.000420382,0.01058806,0.0002551641,0.0001039187,0.008611632,0.002222159,0.002022485,0.002995797,0.0001172953],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9835271,0.01258428,0.000719269,0.0003711387,0.0001523425,0.0002276993,0.0005354863,0.00002925197,0.001853392],"genre_scores_gemma":[0.996057,0.001541703,0.0004589029,0.000630838,0.0001663484,0.000141048,0.0006308488,0.000006990696,0.0003663317],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003537666,"threshold_uncertainty_score":0.01870918,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03279375946446031,"score_gpt":0.2967692754357149,"score_spread":0.2639755159712546,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}