{"id":"W4386704372","doi":"","title":"MICROVASCULAR ENDOTHELIAL ACTIVATION/DYSFUNCTION AND DYSREGULATION OF THE ANGIOPOIETIN-TIE2 SYSTEM IN THE PATHOGENESIS OF LIFE-THREATENING INFECTIONS.","year":2023,"lang":"en","type":"article","venue":"PubMed","topic":"Lipid metabolism and disorders","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; University of Toronto; University of Washington","keywords":"Endothelial activation; Angiopoietin; Medicine; Endothelial dysfunction; Angiopoietin receptor; Sepsis; Endothelium; ARDS; Immunology; Septic shock; Pathogenesis; Inflammation; Lung; Internal medicine; Angiogenesis; Vascular endothelial growth factor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002842105,0.0003472369,0.0002756339,0.0005080296,0.0002120877,0.0004550308,0.0002536933,0.0004848047,0.001457655],"category_scores_gemma":[0.000290144,0.00009666508,0.0002596687,0.0003488142,0.0002191178,0.0003887417,0.0003378862,0.0009116139,0.0002390588],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003306911,"about_ca_system_score_gemma":0.0003487178,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004173162,"about_ca_topic_score_gemma":0.0004865547,"domain_scores_codex":[0.9998442,0.00003794661,0.00001330419,0.00002475935,0.00004119624,0.00003849922],"domain_scores_gemma":[0.9998517,0.00001046349,0.00006281585,0.000006472803,0.00002904483,0.00003949893],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003980106,0.001164324,0.09147262,0.005561434,0.0009382812,0.0207826,0.0005872146,0.001502136,0.4610594,0.01622781,0.02181951,0.3749046],"study_design_scores_gemma":[0.0003948187,0.003343545,0.5512974,0.001409804,0.00127637,0.07234264,0.001181116,0.009280051,0.1496718,0.0162484,0.1933847,0.0001693785],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4858623,0.4824858,0.009780049,0.004493559,0.001621683,0.000166296,0.001080128,0.0002329518,0.01427738],"genre_scores_gemma":[0.9101813,0.08100121,0.002195401,0.001039282,0.0005711039,0.0001106695,0.0005345026,0.000009828232,0.004356596],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001457655,"threshold_uncertainty_score":0.004876375,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01430765156404868,"score_gpt":0.194910143305541,"score_spread":0.1806024917414924,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}