{"id":"W4386708530","doi":"10.1016/j.chom.2023.08.006","title":"Spontaneous HIV expression during suppressive ART is associated with the magnitude and function of HIV-specific CD4+ and CD8+ T cells","year":2023,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Oregon National Primate Research Center; National Institutes of Health; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"Biology; Cytotoxic T cell; CD8; T cell; Transcription factor; Phenotype; Transcription (linguistics); Cell biology; Immunology; Molecular biology; Virology; In vitro; Genetics; Antigen; Immune system; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001136127,0.0001850104,0.0002278044,0.00009448277,0.0002971391,0.00002706651,0.0001076115,0.0001439897,0.0004824694],"category_scores_gemma":[0.000009099036,0.0001197665,0.0000409872,0.0001426473,0.0002769075,0.00005307963,0.0001516615,0.0002344722,0.0009128354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003117355,"about_ca_system_score_gemma":0.00002545967,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001005595,"about_ca_topic_score_gemma":0.00001601163,"domain_scores_codex":[0.9989336,0.0001480044,0.0001557178,0.000329451,0.00005320186,0.0003800216],"domain_scores_gemma":[0.999361,0.000198605,0.0001018641,0.0002317798,0.00006733169,0.00003935813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004542455,0.0001005759,0.001111691,0.00003363423,0.0001039515,0.0002562086,0.0009725609,0.000002118787,0.9431408,0.000001321911,0.05363418,0.0001886868],"study_design_scores_gemma":[0.002436925,0.0002658195,0.02625926,0.00009091694,0.00005555791,0.0001876273,0.0006515885,9.70046e-7,0.9399431,0.000003927335,0.02995989,0.0001444567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954758,0.002812467,0.000009044214,0.0002348661,0.00007973089,0.0003438984,0.0003534716,0.00004939026,0.0006413903],"genre_scores_gemma":[0.9694644,0.0009769411,0.00001271749,0.00003086033,0.00001270804,0.00002111014,0.0004219455,0.0000219236,0.02903746],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02839606,"threshold_uncertainty_score":0.9998651,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006835891465720098,"score_gpt":0.1980365259720481,"score_spread":0.191200634506328,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}