{"id":"W4386708530","doi":"10.1016/j.chom.2023.08.006","title":"Spontaneous HIV expression during suppressive ART is associated with the magnitude and function of HIV-specific CD4+ and CD8+ T cells","year":2023,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Oregon National Primate Research Center; National Institutes of Health; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"Biology; Cytotoxic T cell; CD8; T cell; Transcription factor; Phenotype; Transcription (linguistics); Cell biology; Immunology; Molecular biology; Virology; In vitro; Genetics; Antigen; Immune system; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002923275,0.0001504,0.0002755956,0.0005305624,0.0002601914,0.0006731389,0.0002162795,0.0003019388,0.001994088],"category_scores_gemma":[0.001106651,0.0001821914,0.0001298585,0.0003518177,0.0002809541,0.0003186137,0.0002843482,0.0003830293,0.0003068536],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001797428,"about_ca_system_score_gemma":0.0001251185,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006254906,"about_ca_topic_score_gemma":0.0005332289,"domain_scores_codex":[0.9996995,0.00005104659,0.00002228275,0.00007320983,0.00008367311,0.0000703057],"domain_scores_gemma":[0.9994798,0.0001372162,0.0001634893,0.00006233545,0.00008073341,0.00007645268],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001460289,0.0001409689,0.5099766,0.0001284261,0.00006472173,0.0005236196,0.0007748552,0.0002686275,0.4485253,0.0002191501,0.0003399485,0.03757749],"study_design_scores_gemma":[0.00001348345,0.0004038127,0.9473994,0.00001759288,0.00006164586,0.001974699,0.0004103123,0.001070092,0.04742805,0.0003439878,0.0008634123,0.00001346625],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980634,0.0004638976,0.0005018038,0.00002445607,0.000003648821,0.000008846697,0.0001667913,0.00002819653,0.0007390174],"genre_scores_gemma":[0.9992636,0.00008377664,0.0002423705,0.00001536277,0.000009250391,0.00001160668,0.0001476858,0.000005577319,0.0002207536],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001994088,"threshold_uncertainty_score":0.006670833,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006835891465720098,"score_gpt":0.1980365259720481,"score_spread":0.191200634506328,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}