{"id":"W4386716649","doi":"10.1039/d3ra03907b","title":"pH-Sensitive nanodiamond co-delivery of retinal and doxorubicin boosts breast cancer chemotherapy","year":2023,"lang":"en","type":"article","venue":"RSC Advances","topic":"Nanoplatforms for cancer theranostics","field":"Engineering","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"China Institute of Radiation Protection; China Atomic Energy Authority; Natural Science Foundation of Shanxi Province; Shanxi University","keywords":"Nanodiamond; Doxorubicin; Breast cancer; Chemotherapy; Retinal; Cancer research; Chemistry; Medicine; Cancer; Internal medicine; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005113413,0.0001960316,0.0001550694,0.0001233946,0.00008152267,0.0001547339,0.0001273049,0.0002471049,0.0009537616],"category_scores_gemma":[0.00008642437,0.0001004046,0.0001551938,0.00007104643,0.0001295852,0.0001484399,0.0001408252,0.0002298157,0.0002536299],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003541372,"about_ca_system_score_gemma":0.0001872258,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007550681,"about_ca_topic_score_gemma":0.001223236,"domain_scores_codex":[0.9999546,0.000003447815,0.000003068604,0.00001404409,0.00001262049,0.00001216643],"domain_scores_gemma":[0.9999701,0.000006482607,0.000009255651,0.000003785475,0.000004319485,0.000006021366],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003787399,0.00001622843,0.00004320386,0.00002969695,0.000001913832,0.00003246679,0.000007531068,0.0001184028,0.9964795,0.0001465346,0.00006028111,0.003026347],"study_design_scores_gemma":[0.000003578736,0.00005247727,0.0002533037,0.000001456621,0.000002935983,0.0000494362,0.000002449035,0.001381952,0.9971372,0.00001726091,0.001095649,0.000002230376],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9813765,0.001743027,0.01106431,0.0001507929,0.00007162408,0.00006099253,0.000131177,0.0002605848,0.005140934],"genre_scores_gemma":[0.9916148,0.0005071649,0.005417366,0.0000378452,0.000005370785,0.00001693863,0.00005170054,0.00001618986,0.002332613],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009537616,"threshold_uncertainty_score":0.003190637,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007002013200126701,"score_gpt":0.2413977276290906,"score_spread":0.2343957144289639,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}