{"id":"W4386726664","doi":"10.1002/advs.202301985","title":"Red Light‐Triggered Anti‐Angiogenic and Photodynamic Combination Therapy of Age‐Related Macular Degeneration","year":2023,"lang":"en","type":"article","venue":"Advanced Science","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital","funders":"Young Scientists Fund; National Natural Science Foundation of China","keywords":"Photodynamic therapy; Macular degeneration; Verteporfin; Choroidal neovascularization; Medicine; Prodrug; Photosensitizer; Combination therapy; Neovascularization; Cancer research; Pharmacology; Angiogenesis; Ophthalmology; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000128467,0.00007880128,0.0001377332,0.0001761062,0.0001156677,0.00001323178,0.00006136281,0.00002510905,0.00001090583],"category_scores_gemma":[0.00004912394,0.00006233358,0.00004788525,0.001048254,0.0001565119,0.0001646985,0.00002002276,0.00002943233,0.000009983773],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003525064,"about_ca_system_score_gemma":0.00005503672,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000705943,"about_ca_topic_score_gemma":9.167174e-7,"domain_scores_codex":[0.9991507,0.00001532453,0.000151441,0.000241179,0.0002847893,0.0001565695],"domain_scores_gemma":[0.9995621,0.00001541741,0.00007222527,0.0001701101,0.00009879279,0.00008139631],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00006004941,0.0000774354,0.005511003,0.00001114235,0.00001830645,0.00003950378,0.00008544347,0.00009706842,0.9854717,0.0003882486,0.000007633736,0.008232442],"study_design_scores_gemma":[0.003682011,0.0005236436,0.6440335,0.00008580919,0.00004592083,0.0000217361,0.0000548822,0.0121161,0.3370944,0.002067461,0.0001463269,0.000128183],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982995,0.0005487405,0.0000309821,0.0002856842,0.00007533121,0.0003515186,0.00000381952,0.0000528023,0.0003516366],"genre_scores_gemma":[0.9981319,0.001189621,0.0003421456,0.00002823437,0.000003889135,0.00001404607,0.00004853332,0.000007608421,0.0002340188],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6483773,"threshold_uncertainty_score":0.254189,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0115032444630465,"score_gpt":0.2935893897939501,"score_spread":0.2820861453309035,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}