{"id":"W4386726830","doi":"10.1002/adhm.202301815","title":"Multimodal Imaging of Pancreatic Cancer Microenvironment in Response to an Antiglycolytic Drug","year":2023,"lang":"en","type":"article","venue":"Advanced Healthcare Materials","topic":"Spectroscopy Techniques in Biomedical and Chemical Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Division of Chemical, Bioengineering, Environmental, and Transport Systems; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; Nutrition Obesity Research Center, University of North Carolina; National Institutes of Health; National Science Foundation","keywords":"Pancreatic cancer; Tumor microenvironment; Cancer research; Cancer; Molecular imaging; Cancer cell; Fluorescence-lifetime imaging microscopy; Metastasis; Microscopy; Biomarker discovery; Chemistry; Medicine; Materials science; Pathology; Biology; Biochemistry; Fluorescence; Proteomics; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001173269,0.0001880277,0.0001224043,0.0003511241,0.00009481774,0.0001641227,0.0001184587,0.0003113927,0.0007946445],"category_scores_gemma":[0.00007617101,0.000111737,0.0001261571,0.0001825637,0.0001147601,0.0002135906,0.0001589563,0.0002781068,0.0001208092],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001397818,"about_ca_system_score_gemma":0.00009890513,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003940982,"about_ca_topic_score_gemma":0.0005400525,"domain_scores_codex":[0.9999548,0.000008088057,0.000001857872,0.00001342268,0.00001101706,0.00001073914],"domain_scores_gemma":[0.9999635,0.000009165241,0.00001075805,0.00000251906,0.000006861956,0.000007122455],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007952254,0.000009952018,0.0002499849,0.00002522996,0.000003584076,0.00005673819,0.00001600919,0.00009899232,0.9977246,0.00003678609,0.0000359624,0.001662582],"study_design_scores_gemma":[0.00001155772,0.0002210633,0.007302995,0.000006258227,0.00002615532,0.0003530319,0.00006337649,0.006550506,0.9844031,0.00007456631,0.0009793666,0.0000081343],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9817343,0.001561409,0.01413097,0.000162024,0.00001407259,0.00002362962,0.000279429,0.000182804,0.001911432],"genre_scores_gemma":[0.9779363,0.001293003,0.01763879,0.0001395333,0.00001358625,0.00006693922,0.0002244683,0.00002943665,0.002657732],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007946445,"threshold_uncertainty_score":0.002658367,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01160984080999418,"score_gpt":0.3720164299755486,"score_spread":0.3604065891655545,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}