{"id":"W4386757241","doi":"10.1007/s11748-023-01971-2","title":"Real-world safety and effectiveness of inhaled nitric oxide therapy for pulmonary hypertension during the perioperative period of cardiac surgery: a post-marketing study of 2817 patients in Japan","year":2023,"lang":"en","type":"article","venue":"General Thoracic and Cardiovascular Surgery","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Mallinckrodt Pharmaceuticals","keywords":"Medicine; Perioperative; Fraction of inspired oxygen; Anesthesia; Blood pressure; Pulmonary hypertension; Adverse effect; Cardiac surgery; Methemoglobin; Oxygenation; Surgery; Cardiology; Internal medicine; Hemoglobin; Mechanical ventilation","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001678706,0.0003530222,0.0006892984,0.0003476067,0.000409837,0.0006346829,0.0002195948,0.000434447,0.0007411022],"category_scores_gemma":[0.00357584,0.0002887223,0.000723857,0.0004265879,0.0005094398,0.0004213604,0.0003087596,0.000542649,0.0001465777],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005579827,"about_ca_system_score_gemma":0.0005508691,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00110893,"about_ca_topic_score_gemma":0.001198771,"domain_scores_codex":[0.9986638,0.0004897922,0.0001806312,0.0002528469,0.0003159489,0.00009702965],"domain_scores_gemma":[0.9936912,0.0009619558,0.003773637,0.0003979621,0.0006059457,0.0005693217],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003653906,0.0006634966,0.98708,0.00008985278,0.0003492741,0.0002035786,0.0003176618,0.00008253507,0.001324656,0.00001272832,0.0001508477,0.006071383],"study_design_scores_gemma":[0.0004373349,0.008394054,0.9888602,0.00001227812,0.0002731317,0.0003851987,0.0002869162,0.0003597522,0.0004655081,0.00001007052,0.0004999382,0.00001560161],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995864,0.0001621089,0.00003754351,0.00001382457,0.000003337191,0.00001954937,0.00007731182,9.859443e-7,0.00009895927],"genre_scores_gemma":[0.9993856,0.0001354907,0.00008117154,0.00006687791,0.0000253663,0.00002938891,0.000204801,0.000001541254,0.00006985995],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001678706,"threshold_uncertainty_score":0.008877933,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02217577425137831,"score_gpt":0.2769584237291686,"score_spread":0.2547826494777903,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}