{"id":"W4386761689","doi":"10.1101/2023.09.14.557721","title":"The ALDH1A3 Reporter Construct: A Novel Mechanism of Identifying and Tracking the Breast Cancer Stem Cell Population","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Windsor","funders":"University of Windsor","keywords":"Cancer stem cell; Breast cancer; Stem cell; Cancer research; Population; Biology; Cancer; Mechanism (biology); Stem cell marker; Pathology; Medicine; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000582416,0.0003665125,0.000348431,0.0005344513,0.0003247131,0.0007949038,0.0005168587,0.0006875883,0.002049627],"category_scores_gemma":[0.0003318394,0.0003074009,0.0003632944,0.0003652039,0.000654044,0.0003799745,0.0006417576,0.001723482,0.0009585429],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004653692,"about_ca_system_score_gemma":0.0004480798,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006510231,"about_ca_topic_score_gemma":0.0007855514,"domain_scores_codex":[0.9997112,0.00003463433,0.00001888838,0.00009783864,0.0001007674,0.00003667805],"domain_scores_gemma":[0.9997409,0.00006211711,0.00006510271,0.0000359339,0.00003348322,0.00006248954],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005960252,0.00002385967,0.0001371566,0.00002201952,0.000003882823,0.00003987398,0.00003041836,0.00008729751,0.9960967,0.001015406,0.0001953302,0.002288445],"study_design_scores_gemma":[0.00001295529,0.00004267375,0.000426414,0.000004833953,0.00000593977,0.0001429407,0.00001263259,0.001461959,0.9923365,0.0001947653,0.005350359,0.00000811132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5344427,0.001437383,0.4489602,0.001618529,0.0003718346,0.000385654,0.002765941,0.002978181,0.007039495],"genre_scores_gemma":[0.797915,0.001028254,0.1820147,0.000423425,0.00005855528,0.0004033523,0.002109191,0.0007408943,0.01530661],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002049627,"threshold_uncertainty_score":0.00685668,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03590224839661815,"score_gpt":0.2615747013971613,"score_spread":0.2256724530005432,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}