{"id":"W4386784019","doi":"10.1158/1557-3265.aacrahns23-pr05","title":"Abstract PR05: Changing the radiation and immune-oncology paradigm in patients with head and neck squamous cell carcinoma (HNSCC) with the radioenhancer NBTXR3: From bench to bedside","year":2023,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Oncology; Head and neck squamous-cell carcinoma; Internal medicine; Radiation therapy; Cancer; Abscopal effect; Head and neck cancer; Immunotherapy; Cancer research","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003686179,0.0001733662,0.0003181897,0.0001336353,0.0002250287,0.0003662052,0.0002833161,0.000293805,0.002852194],"category_scores_gemma":[0.0001940097,0.00008506164,0.0003278233,0.0001800036,0.0002095823,0.0002964177,0.0001953149,0.0004206119,0.0005993567],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000591542,"about_ca_system_score_gemma":0.0008519547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001743089,"about_ca_topic_score_gemma":0.004528845,"domain_scores_codex":[0.9998925,0.00002446703,0.000008245524,0.0000252179,0.00002110876,0.00002853277],"domain_scores_gemma":[0.9999282,0.000008296238,0.00001177087,0.000005095726,0.00001231447,0.00003424802],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.03684423,0.004747564,0.202343,0.001263642,0.0002427338,0.002146618,0.0003475357,0.001356645,0.2440011,0.0005084012,0.01886873,0.4873299],"study_design_scores_gemma":[0.005555618,0.0986267,0.76058,0.0002584055,0.0008318824,0.008775586,0.0008981513,0.003705359,0.07907682,0.0004308378,0.04121185,0.00004877265],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897808,0.00410614,0.0005731015,0.0007728231,0.00009181374,0.0002424716,0.000533759,0.00007847854,0.003820716],"genre_scores_gemma":[0.9945815,0.001219743,0.00119702,0.0004461542,0.00005140792,0.00009087048,0.0008123674,0.0000110869,0.001589674],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002852194,"threshold_uncertainty_score":0.009541571,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1009043969158615,"score_gpt":0.466549319914253,"score_spread":0.3656449229983915,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}