{"id":"W4386784091","doi":"10.1158/1557-3265.aacrahns23-pr10","title":"Abstract PR10: A decade in the making: Screening ctDNA detection in HPV-associated HNSCC","year":2023,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Molecular Biology Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Digital polymerase chain reaction; Medicine; Biobank; Head and neck squamous-cell carcinoma; Internal medicine; Oncology; Liquid biopsy; Cancer; Head and neck cancer; Bioinformatics; Biology; Polymerase chain reaction; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01143878,0.0006061161,0.0006315825,0.0008263018,0.0004031861,0.003056861,0.0009494672,0.001987677,0.003193752],"category_scores_gemma":[0.008018098,0.0002907393,0.0002970953,0.000630524,0.001306631,0.003074738,0.001129559,0.002784744,0.001078325],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001234105,"about_ca_system_score_gemma":0.001895762,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001504752,"about_ca_topic_score_gemma":0.00176303,"domain_scores_codex":[0.9982458,0.0005997533,0.0002009518,0.0003393875,0.0004650996,0.0001490201],"domain_scores_gemma":[0.9941449,0.001611361,0.0005467884,0.0003912591,0.002327403,0.0009782509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.001704164,0.0002850549,0.07497655,0.001071498,0.00012284,0.0008042639,0.0009315133,0.0008193307,0.04989584,0.005905435,0.05441633,0.8090671],"study_design_scores_gemma":[0.0001973851,0.006506741,0.1125055,0.003293545,0.000330872,0.01223368,0.00455784,0.00543517,0.0672757,0.01147126,0.7758828,0.0003094475],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.3256192,0.3689813,0.04657264,0.2058728,0.02250191,0.0002731808,0.001415,0.001384176,0.02737981],"genre_scores_gemma":[0.7202914,0.1409384,0.04186673,0.05467359,0.01266645,0.0001759319,0.001482174,0.0003677232,0.02753763],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01143878,"threshold_uncertainty_score":0.06049484,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2335351691490474,"score_gpt":0.5510196840192118,"score_spread":0.3174845148701644,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}