{"id":"W4386784328","doi":"10.1158/1557-3265.aacrahns23-po-046","title":"Abstract PO-046: Relationship of HPV16 E6 seropositivity with circulating tumor tissue modified HPV DNA before head and neck cancer diagnosis","year":2023,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Head and Neck Cancer Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Serology; Cancer; Incidence (geometry); Biomarker; Head and neck cancer; Oncology; Population; Internal medicine; Antibody; Multiplex; Disease; Antigen; Pathology; Immunology; Bioinformatics; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049384,0.0002158177,0.0002094579,0.0007239035,0.0003830706,0.0006772514,0.0004658873,0.000657377,0.007410439],"category_scores_gemma":[0.003629584,0.0002377565,0.0002189311,0.0007017998,0.0002434512,0.0005340582,0.0003278571,0.0009977126,0.0009124138],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002747809,"about_ca_system_score_gemma":0.0003066641,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002926693,"about_ca_topic_score_gemma":0.001442183,"domain_scores_codex":[0.9996687,0.00006279807,0.00003222306,0.0001087248,0.00005496381,0.00007265076],"domain_scores_gemma":[0.9971803,0.0008615255,0.001016732,0.0001655046,0.0003230272,0.0004529383],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004608477,0.00004700407,0.9978132,0.00001044339,0.00001711933,0.0001176961,0.00002822433,0.00002630596,0.0004357769,0.00001085299,0.0001463507,0.000886143],"study_design_scores_gemma":[0.00001092435,0.0002785044,0.9981788,0.000006127281,0.00002098613,0.0004953513,0.0001242969,0.000229479,0.0003188793,0.00002265515,0.0003108619,0.000003109852],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975726,0.0002223005,0.0001498958,0.00006387642,0.0000231978,0.00001699405,0.0009025239,0.00001533818,0.001033304],"genre_scores_gemma":[0.9990086,0.00003207452,0.00007308623,0.00001806442,0.00001485947,0.00001175033,0.0003887764,0.000003465721,0.0004493778],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007410439,"threshold_uncertainty_score":0.02479041,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3110364928825635,"score_gpt":0.5347342473916546,"score_spread":0.2236977545090912,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}