{"id":"W4386784348","doi":"10.1158/1557-3265.aacrahns23-po-061","title":"Abstract PO-061: Utilizing T cell receptor-based therapy to treat anaplastic thyroid cancer","year":2023,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"vaccines and immunoinformatics approaches","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Epitope; Biology; Cancer research; Chimeric antigen receptor; Major histocompatibility complex; Antigen; Cancer; Immunotherapy; Immunology; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001598585,0.0001976289,0.0002682609,0.0001441593,0.0002133075,0.00008810929,0.000521717,0.0002416702,0.0004064676],"category_scores_gemma":[0.0003136561,0.0001610219,0.0001861858,0.000617335,0.0001159185,0.000008034686,0.0002251356,0.0004667605,0.0003308074],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005829923,"about_ca_system_score_gemma":0.0005428303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003497802,"about_ca_topic_score_gemma":0.000126922,"domain_scores_codex":[0.9976804,0.0001418647,0.0005324799,0.0005077728,0.0004196196,0.0007178086],"domain_scores_gemma":[0.9985325,0.0002501632,0.0000800843,0.0005850051,0.0002734478,0.000278764],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003162265,0.0003964693,0.01504727,0.0002613127,0.0001168632,0.000007871108,0.0001699279,0.00212689,0.5845152,0.00002173499,0.271618,0.1225561],"study_design_scores_gemma":[0.005623353,0.003886197,0.05912742,0.0001933762,0.00002165867,8.454251e-7,0.0009012757,0.001465771,0.5146335,0.00005776799,0.4132204,0.0008683902],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920144,0.002548709,0.000028743,0.001710675,0.0003476619,0.0004809927,0.0000885597,0.00003710504,0.002743144],"genre_scores_gemma":[0.9861605,0.01019233,0.0001183137,0.0005702659,0.000697148,0.0003330036,0.0001339907,0.00005187554,0.001742592],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1416024,"threshold_uncertainty_score":0.6566284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2196595809791004,"score_gpt":0.4733704058011066,"score_spread":0.2537108248220062,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}