{"id":"W4386784744","doi":"10.1158/1557-3265.aacrahns23-po-070","title":"Abstract PO-070: New patient-derived head and neck cancer xenograft (PDX) panel for drug development, immuno-oncology and translational research","year":2023,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Cetuximab; Medicine; Head and neck squamous-cell carcinoma; Oncology; Radiation therapy; Internal medicine; Head and neck cancer; Docetaxel; Cancer; Cancer research; Colorectal cancer","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007397216,0.0004205351,0.0004169744,0.0003585258,0.0002250815,0.000430012,0.0003723906,0.0003923259,0.002603309],"category_scores_gemma":[0.000204728,0.0001689143,0.0003942024,0.0003146176,0.0001614386,0.0002293254,0.000310798,0.001022088,0.0008321707],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002953277,"about_ca_system_score_gemma":0.0003754628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008670379,"about_ca_topic_score_gemma":0.001003908,"domain_scores_codex":[0.9996716,0.00006123761,0.00003089351,0.00006592456,0.0001154409,0.00005491147],"domain_scores_gemma":[0.99981,0.00003048358,0.00001810141,0.00004422005,0.00004718373,0.00004996001],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001053927,0.00103754,0.004384592,0.0001121101,0.00006086486,0.0002181037,0.00006276477,0.001057955,0.9761677,0.0003438304,0.003353482,0.01214708],"study_design_scores_gemma":[0.0004319843,0.01108483,0.03786018,0.00004223685,0.00026517,0.003521906,0.0001213312,0.006872464,0.9049464,0.0002402775,0.03458277,0.00003055684],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.9746087,0.001883438,0.007861411,0.0002320407,0.00009162202,0.0007245214,0.009329636,0.0002482101,0.005020351],"genre_scores_gemma":[0.9322167,0.001864483,0.01729268,0.0003765122,0.00002934852,0.0008729801,0.04128267,0.00007708847,0.005987544],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.002603309,"threshold_uncertainty_score":0.008708954,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.358769073137913,"score_gpt":0.5591379491896306,"score_spread":0.2003688760517176,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}