{"id":"W4386784884","doi":"10.1158/1557-3265.aacrahns23-po-023","title":"Abstract PO-023: The AP-1 transcription factor component, JunB, regulates the expression of HPV genes in head and neck cancer","year":2023,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Cancer research; Head and neck squamous-cell carcinoma; Medicine; Cancer; Demethylating agent; Oncology; Head and neck cancer; Internal medicine; Biology; DNA methylation; Gene expression; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001013643,0.0002224821,0.0001154361,0.0001726785,0.0002512527,0.0003053163,0.0002113114,0.0002411716,0.004477296],"category_scores_gemma":[0.00009082154,0.000093892,0.000191907,0.0001484552,0.0001628556,0.0001605944,0.0001618282,0.0005286361,0.001070449],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002980354,"about_ca_system_score_gemma":0.0002058099,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007343517,"about_ca_topic_score_gemma":0.0007125896,"domain_scores_codex":[0.9999186,0.000009146685,0.000005455697,0.00002312297,0.0000256634,0.00001802324],"domain_scores_gemma":[0.9999462,0.000006453572,0.00001124703,0.000004762925,0.00001392902,0.00001744521],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002940971,0.00005668711,0.0009472902,0.00006759114,0.000005427401,0.00004809348,0.00001448478,0.00002203498,0.9956797,0.00006859592,0.0001787938,0.00261721],"study_design_scores_gemma":[0.00007504066,0.0007234171,0.06839792,0.0000311008,0.00005056775,0.00077732,0.0001706412,0.001219337,0.918748,0.0001692361,0.009631297,0.000006214955],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9843706,0.008053448,0.001683806,0.0003453535,0.000139526,0.00004309971,0.00123387,0.00009668604,0.004033566],"genre_scores_gemma":[0.9871573,0.001500586,0.0008717199,0.0001584981,0.00002269368,0.00003825396,0.001671425,0.0000223822,0.008557051],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004477296,"threshold_uncertainty_score":0.01497805,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2356690672445588,"score_gpt":0.4925662273740856,"score_spread":0.2568971601295268,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}