{"id":"W4386800242","doi":"10.1016/bs.irn.2023.08.011","title":"Cholesterol alterations in fragile X syndrome, autism spectrum disorders and other neurodevelopmental disorders","year":2023,"lang":"en","type":"review","venue":"International review of neurobiology","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Fragile X syndrome; Autism; Autism spectrum disorder; Neurodevelopmental disorder; Neuroscience; Psychology; Rett syndrome; Medicine; Psychiatry; Biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005721865,0.0009723902,0.001937758,0.002661164,0.000232411,0.001048843,0.0007992427,0.001084311,0.00276961],"category_scores_gemma":[0.0007616027,0.0002700584,0.0004550302,0.003038869,0.0003989473,0.0009729411,0.0008108775,0.001332069,0.001410283],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005363653,"about_ca_system_score_gemma":0.001266557,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001812473,"about_ca_topic_score_gemma":0.003169044,"domain_scores_codex":[0.9998,0.00003302018,0.00003630613,0.00003285884,0.00007891302,0.00001883367],"domain_scores_gemma":[0.9997683,0.0001000287,0.00004267829,0.000006213479,0.00005947725,0.0000233425],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001576137,0.00005001617,0.0003387515,0.01503606,0.0001634646,0.0004900235,0.00003065327,0.0002423014,0.001656585,0.002120542,0.03808016,0.9416337],"study_design_scores_gemma":[0.00006905548,0.0001005449,0.0021175,0.004654393,0.0004377198,0.003474219,0.00007139323,0.0001151348,0.0005299936,0.002531093,0.9858649,0.00003406121],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004740814,0.9993993,0.00005596692,0.000109237,0.0001040129,0.000001768949,0.00001513303,0.000003758716,0.0002634078],"genre_scores_gemma":[0.0002823319,0.9991448,0.00009117935,0.00009402086,0.0001597646,0.000002652462,0.00002666296,6.692443e-7,0.0001979582],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00276961,"threshold_uncertainty_score":0.009265304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01905613287027303,"score_gpt":0.3065149160348694,"score_spread":0.2874587831645964,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}