{"id":"W4386824954","doi":"10.1089/can.2023.0045","title":"Chemistry, Crystal Structure, and <i>In Vitro</i> Receptor Binding of Δ10-THC Isomers","year":2023,"lang":"en","type":"article","venue":"Cannabis and Cannabinoid Research","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Smiths Detection (Canada)","funders":"","keywords":"Chemistry; Cannabinoid; Radioligand; Stereochemistry; Agonist; Cis–trans isomerism; Receptor; IC50; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001270382,0.0003957408,0.0002469438,0.0001186433,0.0002363503,0.0003663623,0.0007406919,0.0002197584,0.003256412],"category_scores_gemma":[0.0002488581,0.0002038755,0.0001966844,0.0002792301,0.0002088837,0.0001407056,0.0001312106,0.0007156255,0.001103783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008418101,"about_ca_system_score_gemma":0.0007328567,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01134183,"about_ca_topic_score_gemma":0.009330649,"domain_scores_codex":[0.9998829,0.000008700243,0.00000658014,0.00002498422,0.00005488564,0.00002203677],"domain_scores_gemma":[0.9999224,0.00001268991,0.00002145282,0.000004876455,0.00002480248,0.00001375526],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006617203,0.0001715739,0.003624936,0.001311194,0.00006881875,0.0005808557,0.0001194657,0.004596625,0.9644438,0.001881403,0.005655658,0.01688386],"study_design_scores_gemma":[0.00019644,0.0005653546,0.008555467,0.00008426627,0.0001208466,0.001306194,0.0002043187,0.0116052,0.9304541,0.0005176016,0.04633196,0.00005824453],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9639817,0.0127874,0.006238058,0.000593881,0.0002012596,0.00009046755,0.004444846,0.0002855584,0.01137683],"genre_scores_gemma":[0.9637288,0.01062182,0.00758475,0.0003570307,0.0000757606,0.00008303297,0.008477675,0.00009078415,0.008980318],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01134183,"threshold_uncertainty_score":0.02255166,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02598467995056138,"score_gpt":0.3247684644642331,"score_spread":0.2987837845136717,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}