{"id":"W4386824954","doi":"10.1089/can.2023.0045","title":"Chemistry, Crystal Structure, and <i>In Vitro</i> Receptor Binding of Δ10-THC Isomers","year":2023,"lang":"en","type":"article","venue":"Cannabis and Cannabinoid Research","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Smiths Detection (Canada)","funders":"","keywords":"Chemistry; Cannabinoid; Radioligand; Stereochemistry; Agonist; Cis–trans isomerism; Receptor; IC50; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001951847,0.0003725516,0.0007654903,0.00114271,0.0003123118,0.0001180862,0.0002926839,0.0003545881,0.000384162],"category_scores_gemma":[0.0006148388,0.0003363285,0.0001411336,0.002943683,0.001304437,0.0001551052,0.0005164548,0.001244581,0.00002007221],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002870655,"about_ca_system_score_gemma":0.0009115994,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008484014,"about_ca_topic_score_gemma":0.00006453044,"domain_scores_codex":[0.9951482,0.0002098164,0.000644374,0.0009703083,0.001486934,0.00154041],"domain_scores_gemma":[0.9977391,0.00003618506,0.0001008674,0.000614157,0.0006622103,0.0008474747],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006281273,0.0000791747,0.003668847,0.001228402,0.00004224597,0.0001011314,0.0005319028,0.000004247722,0.8095838,0.00004447219,0.1757258,0.008361801],"study_design_scores_gemma":[0.004679236,0.0006630542,0.05833761,0.0003894989,0.00004465265,0.0002068535,0.005290552,0.0006866139,0.5873503,0.000256882,0.341344,0.0007507535],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9767749,0.001956878,9.327122e-7,0.01827388,0.0001136045,0.0009114437,0.0003972092,0.00007129574,0.001499884],"genre_scores_gemma":[0.9470944,0.001461942,0.0000495786,0.00009669842,0.0002343702,0.0001991912,0.0002148622,0.00009648391,0.05055247],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2222335,"threshold_uncertainty_score":0.9999089,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02598467995056138,"score_gpt":0.3247684644642331,"score_spread":0.2987837845136717,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}