{"id":"W4386851661","doi":"10.1016/j.isci.2023.107968","title":"Schlafen-5 inhibits LINE-1 retrotransposition","year":2023,"lang":"en","type":"article","venue":"iScience","topic":"Chromosomal and Genetic Variations","field":"Agricultural and Biological Sciences","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital","funders":"China Scholarship Council; Chinese Academy of Medical Sciences Initiative for Innovative Medicine; National Natural Science Foundation of China","keywords":"Retrotransposon; Ribonucleoprotein; Biology; RNA Helicase A; Cell biology; RNA; Helicase; RNA interference; Genetics; Cell culture; Transposable element; Genome; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000770642,0.000205285,0.0001317653,0.0001281835,0.00008630372,0.0001283126,0.0001360222,0.0001756975,0.001349036],"category_scores_gemma":[0.0001038485,0.00004526183,0.0001220014,0.00004790899,0.0001261526,0.00007704524,0.0001061679,0.0002674519,0.0001924162],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001778097,"about_ca_system_score_gemma":0.0001370646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005950298,"about_ca_topic_score_gemma":0.001064155,"domain_scores_codex":[0.9999239,0.00001751442,0.00000631199,0.000009922704,0.00001888581,0.00002340919],"domain_scores_gemma":[0.999935,0.00002163169,0.00001467375,0.000005383613,0.000004178288,0.00001915383],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003363383,0.0001102159,0.0007726133,0.00003833468,0.000008320952,0.00005914509,0.00001923303,0.0001287454,0.9942427,0.0001296284,0.00009702944,0.004057593],"study_design_scores_gemma":[0.0000331833,0.001554157,0.008455499,0.000008760793,0.00001404571,0.0002022082,0.00002913091,0.001390303,0.9853545,0.00006045616,0.00289346,0.000004254983],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961578,0.001054622,0.0008812394,0.0000751393,0.00002685139,0.00001381754,0.0001562515,0.00004663575,0.001587567],"genre_scores_gemma":[0.997381,0.0003230081,0.0005670002,0.000038861,0.000006248307,0.000008101487,0.0002735054,0.000004683293,0.001397528],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001349036,"threshold_uncertainty_score":0.004512966,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02823940030298048,"score_gpt":0.2373145124427442,"score_spread":0.2090751121397637,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}