{"id":"W4386852251","doi":"10.1016/j.dci.2023.105064","title":"Pentraxins in invertebrates and vertebrates: From structure, function and evolution to clinical applications","year":2023,"lang":"en","type":"review","venue":"Developmental & Comparative Immunology","topic":"Biomarkers in Disease Mechanisms","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Ocean University of China; University of Alberta","keywords":"PTX3; Innate immune system; Biology; Serum amyloid P component; Acquired immune system; Complement system; Immune system; Function (biology); Immunity; Complement receptor; Pattern recognition receptor; Ficolin; Computational biology; Immunology; Inflammation; Cell biology; C-reactive protein","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002378832,0.0005780596,0.001797609,0.00051835,0.000226243,0.00003718151,0.0003386452,0.0009390295,0.0002228145],"category_scores_gemma":[0.00005562631,0.0005357647,0.0001119219,0.0006147912,0.0005456805,0.000106998,0.0005893105,0.0007716409,0.00140437],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003213852,"about_ca_system_score_gemma":0.000375304,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001534376,"about_ca_topic_score_gemma":0.0006168539,"domain_scores_codex":[0.9964805,0.000849175,0.001103843,0.001054621,0.00004761067,0.0004642574],"domain_scores_gemma":[0.9987196,0.0005686877,0.0003120418,0.0002801493,0.00005213928,0.00006735046],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006783034,0.0005690351,0.01045995,0.001678794,0.007739173,0.00002841047,0.001246486,2.905065e-7,0.005202098,0.008348611,0.004258072,0.9597908],"study_design_scores_gemma":[0.002876104,0.0004571348,0.1073522,0.00314905,0.0008596642,0.0001845742,0.001810408,0.000007115669,0.0002222586,0.008193132,0.8732821,0.001606206],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01098206,0.9849541,0.0005566112,0.00002093162,0.001178775,0.001538591,0.0005687089,0.0001233411,0.00007685798],"genre_scores_gemma":[0.01605358,0.9774024,0.0009166828,0.0001352547,0.00005625188,0.001028802,0.004035612,0.00006975353,0.0003016281],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9581845,"threshold_uncertainty_score":0.9997094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08879056077422805,"score_gpt":0.3626927616845104,"score_spread":0.2739022009102823,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}