{"id":"W4386866162","doi":"10.1016/j.cgh.2023.08.041","title":"HLADQA1∗05G&gt;A Genetic Screening Promotes the Safe Delivery of Combination Therapy in Inflammatory Bowel Disease","year":2023,"lang":"en","type":"article","venue":"Clinical Gastroenterology and Hepatology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Academic Medical Organization of Southwestern Ontario","keywords":"Medicine; Inflammatory bowel disease; Disease; Bioinformatics; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004981376,0.0001589662,0.0004257652,0.0002862282,0.0001806612,0.0005231183,0.000159958,0.0004199791,0.003236862],"category_scores_gemma":[0.000717498,0.0000974005,0.0001786213,0.0002182799,0.0002350264,0.0002419247,0.0003499255,0.0006597011,0.0005493414],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002215175,"about_ca_system_score_gemma":0.0002084905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002454256,"about_ca_topic_score_gemma":0.0002981642,"domain_scores_codex":[0.9995821,0.0001722722,0.00001938136,0.00005917567,0.0001064666,0.00006060239],"domain_scores_gemma":[0.9996644,0.0001209151,0.00009015887,0.00003168996,0.00002439278,0.00006833723],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.005466858,0.001053596,0.01625331,0.0001768512,0.0001059959,0.0009300529,0.0001058394,0.001004387,0.8147527,0.001246525,0.002272076,0.1566319],"study_design_scores_gemma":[0.002485012,0.03727812,0.176881,0.0002457099,0.0009350377,0.01943297,0.0003905046,0.01783275,0.6762832,0.004091987,0.06404272,0.0001009588],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9833133,0.003572671,0.006435415,0.001122514,0.0001039524,0.00006624065,0.000131664,0.0001932068,0.005061054],"genre_scores_gemma":[0.9967263,0.0004031285,0.00195618,0.0001410551,0.00003551019,0.0000199677,0.00004267441,0.00001915363,0.0006560296],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003236862,"threshold_uncertainty_score":0.01082838,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02047480396921662,"score_gpt":0.2853372083427684,"score_spread":0.2648624043735517,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}