{"id":"W4386884059","doi":"10.1073/pnas.2308238120","title":"A peptide-binding domain shared with an Antarctic bacterium facilitates <i>Vibrio cholerae</i> human cell binding and intestinal colonization","year":2023,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; Technische Universiteit Eindhoven; Canada Research Chairs; Government of Canada; San Antonio Area Foundation; Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation; Queen's University; Brown Foundation","keywords":"Vibrio cholerae; Biology; Microbiology; Bacterial adhesin; Biofilm; Colonization; Bacteria; Hemagglutinin (influenza); Biochemistry; Escherichia coli; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008816762,0.0002168463,0.0001243968,0.00007488835,0.000134398,0.0002070473,0.0001165848,0.0001530273,0.001085892],"category_scores_gemma":[0.0001062158,0.00008719414,0.0001659432,0.0000690383,0.0001382694,0.00006504175,0.0001666626,0.0002172501,0.0004377661],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002551477,"about_ca_system_score_gemma":0.0002389899,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001936991,"about_ca_topic_score_gemma":0.001476515,"domain_scores_codex":[0.9999398,0.00001363958,0.000003058534,0.00000977644,0.00001638452,0.00001736995],"domain_scores_gemma":[0.999963,0.000006223229,0.000008943606,0.000004136411,0.000006371295,0.00001130777],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001715922,0.00002948617,0.0007933622,0.00006219192,0.000006910173,0.0001036395,0.00001699059,0.00006130029,0.9951492,0.0001196669,0.0001922095,0.003293508],"study_design_scores_gemma":[0.00004270859,0.0009631994,0.0438477,0.00003322167,0.00006978774,0.001690757,0.0001159108,0.001146929,0.9289548,0.00008440492,0.02304045,0.00001015731],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888774,0.003693168,0.001315318,0.0001394176,0.00004526166,0.00003196654,0.0001740843,0.00003127915,0.005692172],"genre_scores_gemma":[0.9923516,0.001746826,0.00193841,0.0001596812,0.000016398,0.00001758228,0.0003971119,0.00001148737,0.003360784],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001936991,"threshold_uncertainty_score":0.003851414,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03426782180278673,"score_gpt":0.3038565001230161,"score_spread":0.2695886783202294,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}