{"id":"W4386892334","doi":"10.21769/bioprotoc.4818","title":"Differentiation of Bone Marrow Monocytes into Alveolar Macrophages-like Cells through Co-culture with Lung Epithelial Cells and Group 2 Innate Lymphoid Cells","year":2023,"lang":"en","type":"article","venue":"BIO-PROTOCOL","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre","funders":"Fonds Léon Fredericq; Université de Liège; Fonds Wetenschappelijk Onderzoek; Vlaamse regering; Fonds De La Recherche Scientifique - FNRS","keywords":"Bone marrow; Immunology; Biology; Innate lymphoid cell; Inflammation; Lung; Embryonic stem cell; Cell biology; Population; Cellular differentiation; Innate immune system; Immune system; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004455931,0.0003583997,0.0002849303,0.0002296945,0.0002479177,0.0003599816,0.0002758603,0.0002657049,0.002345801],"category_scores_gemma":[0.0001289379,0.0001997257,0.0003134431,0.0003031895,0.0001657953,0.0001596362,0.0004461342,0.0006131416,0.002252782],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001361938,"about_ca_system_score_gemma":0.0003127434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005718534,"about_ca_topic_score_gemma":0.001865066,"domain_scores_codex":[0.9993916,0.0001348056,0.00007297109,0.0001205348,0.0001600644,0.000120075],"domain_scores_gemma":[0.9998411,0.00003942148,0.00001856441,0.00003802786,0.0000391739,0.00002365396],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002837465,0.00007705929,0.0005576856,0.0001271374,0.000005595945,0.0001533002,0.00009913716,0.000121622,0.9932835,0.0003112246,0.0002381818,0.004741818],"study_design_scores_gemma":[0.00004252488,0.0003722554,0.003977565,0.00004192976,0.0000227126,0.0002526165,0.00005459839,0.001001416,0.976617,0.00009889679,0.01750937,0.000009188401],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8733925,0.01007342,0.08456886,0.0003750141,0.0003402495,0.00227228,0.004645932,0.0004808494,0.02385094],"genre_scores_gemma":[0.8679957,0.005366151,0.08975139,0.0004471188,0.0001197227,0.002771816,0.007286459,0.0001293759,0.02613223],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002345801,"threshold_uncertainty_score":0.007847488,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009648022433940268,"score_gpt":0.2520972371495295,"score_spread":0.2424492147155892,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}