{"id":"W4386893806","doi":"10.3390/biomedicines11092577","title":"Exogenous OCT4 and SOX2 Contribution to In Vitro Reprogramming in Cattle","year":2023,"lang":"en","type":"article","venue":"Biomedicines","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Faculdade de Medicina da Universidade de São Paulo; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Reprogramming; SOX2; Somatic cell nuclear transfer; Biology; Homeobox protein NANOG; Blastocyst; XIST; Induced pluripotent stem cell; Andrology; Cell biology; Embryonic stem cell; Rex1; Gene expression; Cell; Molecular biology; Gene; Embryo; Genetics; Embryogenesis; Medicine; X-inactivation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003308756,0.0002447499,0.0002526849,0.0002425444,0.0001821063,0.0005014624,0.0001819269,0.0002049958,0.001434906],"category_scores_gemma":[0.0002623666,0.000166994,0.0001955796,0.0001749,0.0001837339,0.0001721416,0.0002663631,0.0003978033,0.0003692356],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003484674,"about_ca_system_score_gemma":0.0002422361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001109434,"about_ca_topic_score_gemma":0.001499834,"domain_scores_codex":[0.9997808,0.00006431669,0.00002387904,0.00004283803,0.00004926678,0.00003894024],"domain_scores_gemma":[0.9998074,0.00006562376,0.00003893645,0.00002620459,0.00001840918,0.0000434522],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001023936,0.00001441134,0.0005257527,0.0000393659,0.000005750591,0.0000702704,0.0000277539,0.00009088255,0.996991,0.0001031625,0.00001599213,0.002013178],"study_design_scores_gemma":[0.00001167538,0.0002318008,0.006504459,0.00001516251,0.00004271362,0.00042588,0.00006619844,0.0008082457,0.9861358,0.00009048987,0.005660541,0.000007032296],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9851353,0.001536738,0.007399263,0.00006507844,0.00003638734,0.00003799505,0.0004137483,0.00005660101,0.005319004],"genre_scores_gemma":[0.985604,0.001863672,0.003782747,0.00005321368,0.00001586324,0.0000372355,0.0009191842,0.00004435344,0.007679647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001434906,"threshold_uncertainty_score":0.0048002,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0157035595014708,"score_gpt":0.2979124707131872,"score_spread":0.2822089112117164,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}