{"id":"W4386894376","doi":"10.3390/cells12182308","title":"Altered Epigenetic Marks and Gene Expression in Fetal Brain, and Postnatal Behavioural Disorders, Following Prenatal Exposure of Ogg1 Knockout Mice to Saline or Ethanol","year":2023,"lang":"en","type":"article","venue":"Cells","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Epigenetics; Biology; DNA methylation; Histone H3; Chromatin immunoprecipitation; Molecular biology; H3K4me3; Histone; Histone methylation; Regulation of gene expression; Gene expression; Cell biology; Genetics; Gene; Promoter","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005978043,0.0003939121,0.0002302846,0.0005945833,0.00013915,0.0001889246,0.0001717906,0.000256375,0.001297034],"category_scores_gemma":[0.00009935632,0.0002461573,0.0001991786,0.0001678027,0.0003474395,0.0001668587,0.0002018868,0.0005629159,0.0002205942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002276794,"about_ca_system_score_gemma":0.0001506332,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001197951,"about_ca_topic_score_gemma":0.002185987,"domain_scores_codex":[0.9998962,0.000005929939,0.00000766129,0.0000449232,0.0000209373,0.00002435877],"domain_scores_gemma":[0.9998608,0.000008966397,0.00007046782,0.000009295062,0.00001233511,0.00003829446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002591887,0.00001892689,0.001173118,0.00002262279,0.000006736829,0.0001214797,0.00004836101,0.00002053554,0.9967405,0.00004365791,0.00002381097,0.001521117],"study_design_scores_gemma":[0.00002207102,0.0005779383,0.1314412,0.00001947629,0.00006857335,0.001253295,0.0002374989,0.0003257075,0.8640333,0.0001637803,0.001841745,0.0000154368],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962441,0.001070899,0.001108241,0.00006095663,0.00001872447,0.000007984851,0.0009207891,0.00008283889,0.0004854418],"genre_scores_gemma":[0.9892134,0.001579431,0.001735596,0.00006963968,0.000009349837,0.0000560688,0.001239296,0.00005666927,0.006040634],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001297034,"threshold_uncertainty_score":0.00433898,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01150813696321317,"score_gpt":0.2598050656151875,"score_spread":0.2482969286519743,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}