{"id":"W4386894376","doi":"10.3390/cells12182308","title":"Altered Epigenetic Marks and Gene Expression in Fetal Brain, and Postnatal Behavioural Disorders, Following Prenatal Exposure of Ogg1 Knockout Mice to Saline or Ethanol","year":2023,"lang":"en","type":"article","venue":"Cells","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Epigenetics; Biology; DNA methylation; Histone H3; Chromatin immunoprecipitation; Molecular biology; H3K4me3; Histone; Histone methylation; Regulation of gene expression; Gene expression; Cell biology; Genetics; Gene; Promoter","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000197458,0.0001546059,0.0001738279,0.00009873186,0.00004189387,0.00001671418,0.00009925966,0.0001595838,0.000006696666],"category_scores_gemma":[0.00008123426,0.0001421357,0.00005086111,0.000130788,0.00004361363,0.000005890882,0.0002256326,0.00007160041,0.000001780888],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005653629,"about_ca_system_score_gemma":0.00002725069,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004450502,"about_ca_topic_score_gemma":0.0001424873,"domain_scores_codex":[0.9989551,0.00007089473,0.0002592721,0.0003699436,0.0001181909,0.000226543],"domain_scores_gemma":[0.9995605,0.00004093691,0.00007656926,0.0001963537,0.00002486588,0.0001008022],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001222755,0.00003043712,0.01045367,0.00003877889,0.00001163314,0.000009862069,0.0003047209,0.00007835171,0.9840998,2.940517e-7,0.00006619793,0.004783954],"study_design_scores_gemma":[0.0008546396,0.0004015092,0.04673273,0.00005119175,0.00001365504,0.000002733795,0.0001288873,0.00009600256,0.9512972,0.00001780049,0.0002266212,0.000177069],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961799,0.002624076,0.0004802662,0.0001318499,0.0001687366,0.0003148963,0.00006884466,0.000009007148,0.00002238992],"genre_scores_gemma":[0.9970415,0.0005928968,0.001619684,0.00004221261,0.00005861358,0.00001684057,0.0002388541,0.00002638958,0.0003629581],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03627906,"threshold_uncertainty_score":0.5796124,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01150813696321317,"score_gpt":0.2598050656151875,"score_spread":0.2482969286519743,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}