{"id":"W4386909796","doi":"10.1001/jamaoncol.2023.3352","title":"Rare Genetic Drivers of Lethal Prostate Cancer","year":2023,"lang":"en","type":"letter","venue":"JAMA Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"","keywords":"Medicine; Otorhinolaryngology; Family medicine; MEDLINE; Neurology; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000127111,0.0002663903,0.0008257679,0.0003339846,0.00004743425,0.00001078304,0.0001914605,0.001178018,0.0007545485],"category_scores_gemma":[0.00006332994,0.0002061301,0.000207706,0.0003045629,0.0003634845,0.0000311155,0.0001317063,0.001751726,0.000207235],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008307347,"about_ca_system_score_gemma":0.001938834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005282091,"about_ca_topic_score_gemma":0.00006630534,"domain_scores_codex":[0.9979533,0.0001475041,0.0003563782,0.0004659568,0.0004693077,0.0006075687],"domain_scores_gemma":[0.9987936,0.000239165,0.0002131128,0.0003689109,0.000279436,0.000105775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004089098,0.00005414406,0.008849871,0.0009515994,0.0004384308,0.01354979,0.0005282181,0.000003995139,0.0004076824,0.00000147374,0.9451361,0.02966974],"study_design_scores_gemma":[0.003865762,0.001358755,0.01117397,0.000339395,0.0003251339,0.0001127802,0.00008118756,0.0000136932,0.0006836837,0.00007299677,0.9817949,0.0001777493],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.059117,0.002643622,0.000001110723,0.9292336,0.001287183,0.001319284,0.0004689304,0.00009761525,0.005831711],"genre_scores_gemma":[0.01036173,0.02027106,0.0008417612,0.6310699,0.01480926,0.001782004,0.003217121,0.0004180027,0.3172292],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.3113975,"threshold_uncertainty_score":0.9085952,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04284164484366915,"score_gpt":0.3671639703383925,"score_spread":0.3243223254947234,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}