{"id":"W4386914078","doi":"10.3389/fpls.2023.1246905","title":"CRISPR/Cas9-mediated lipoxygenase gene-editing in yellow pea leads to major changes in fatty acid and flavor profiles","year":2023,"lang":"en","type":"article","venue":"Frontiers in Plant Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; St. Boniface Hospital; Agriculture and Agri-Food Canada; University of Saskatchewan; University of Calgary; National Research Council Canada","funders":"Biotechnology and Biological Sciences Research Council","keywords":"Lipoxygenase; Polyunsaturated fatty acid; Food science; Hexanal; CRISPR; Biology; Biochemistry; Flavor; Gene; Chemistry; Fatty acid; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002572584,0.0004236478,0.000351243,0.0002175434,0.0002222501,0.0004391558,0.000405961,0.0005365732,0.002480822],"category_scores_gemma":[0.0002133088,0.0001895719,0.000413665,0.0001609284,0.0003263477,0.0002137285,0.0004288071,0.0007551055,0.0007757971],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003357676,"about_ca_system_score_gemma":0.0002553361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001208521,"about_ca_topic_score_gemma":0.001438259,"domain_scores_codex":[0.9997608,0.00001871107,0.00003540086,0.00007255933,0.0000689242,0.00004358643],"domain_scores_gemma":[0.999822,0.00003769071,0.00005174132,0.0000285307,0.00002050174,0.0000395766],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004770069,0.00001248429,0.0001208366,0.00003870365,0.000004745356,0.0001331679,0.00002580359,0.00009006629,0.9983808,0.0001197322,0.00006240864,0.0009635685],"study_design_scores_gemma":[0.00003489224,0.0002250759,0.004810769,0.00001625477,0.00003028841,0.0004752245,0.00007997661,0.003523747,0.9815983,0.0001515498,0.009036208,0.00001776532],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9533626,0.0008197914,0.03533571,0.000241277,0.0001913183,0.0001871964,0.002705157,0.001549309,0.005607736],"genre_scores_gemma":[0.974438,0.0003747426,0.01104611,0.000106311,0.000009109889,0.0001110909,0.001457435,0.000206234,0.01225101],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002480822,"threshold_uncertainty_score":0.008299232,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008227042363293297,"score_gpt":0.2615534587684355,"score_spread":0.2533264164051422,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}