{"id":"W4386914078","doi":"10.3389/fpls.2023.1246905","title":"CRISPR/Cas9-mediated lipoxygenase gene-editing in yellow pea leads to major changes in fatty acid and flavor profiles","year":2023,"lang":"en","type":"article","venue":"Frontiers in Plant Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; St. Boniface Hospital; Agriculture and Agri-Food Canada; University of Saskatchewan; University of Calgary; National Research Council Canada","funders":"Biotechnology and Biological Sciences Research Council","keywords":"Lipoxygenase; Polyunsaturated fatty acid; Food science; Hexanal; CRISPR; Biology; Biochemistry; Flavor; Gene; Chemistry; Fatty acid; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005630699,0.0001362529,0.0001541837,0.0004668712,0.00005096267,0.00003137927,0.0002529035,0.00008336428,0.000001512507],"category_scores_gemma":[0.0003110127,0.0001383351,0.00001460166,0.0008537219,0.000116721,0.000009252132,0.0001727481,0.0001086172,0.000004730994],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003263108,"about_ca_system_score_gemma":0.00005705034,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003742674,"about_ca_topic_score_gemma":0.0007769176,"domain_scores_codex":[0.9986684,0.00002155775,0.000171762,0.0004759383,0.0001722012,0.0004900885],"domain_scores_gemma":[0.9996538,0.00001369083,0.00002670796,0.0001737048,0.00001833437,0.0001137381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002440809,0.00001228232,0.1550723,0.00002838674,0.00000194198,0.00005395033,0.0005366671,0.000790809,0.8399646,0.000001079967,0.002436848,0.001076639],"study_design_scores_gemma":[0.0004259488,0.00008568454,0.1231689,0.00006699838,0.000002144971,0.00001030924,0.0009405767,0.007892226,0.8661014,0.00001001996,0.001055618,0.0002402146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960021,0.0005109115,0.002262986,0.0003099581,0.0005301823,0.0002429204,0.00007063812,0.00001807799,0.00005224884],"genre_scores_gemma":[0.9944639,0.0003202938,0.004779869,0.0001294045,0.00009530626,0.00005212212,0.00007747402,0.00001226375,0.0000694171],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03190348,"threshold_uncertainty_score":0.564114,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008227042363293297,"score_gpt":0.2615534587684355,"score_spread":0.2533264164051422,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}