{"id":"W4386944004","doi":"10.1161/circresaha.123.322516","title":"PPP1R12C Promotes Atrial Hypocontractility in Atrial Fibrillation","year":2023,"lang":"en","type":"article","venue":"Circulation Research","topic":"Atrial Fibrillation Management and Outcomes","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Heart Institute","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Center for Advancing Translational Sciences; Purdue University; European Commission; U.S. Department of Veterans Affairs","keywords":"Atrial fibrillation; Dephosphorylation; Phosphorylation; Internal medicine; Sinus rhythm; Protein subunit; Protein phosphatase 1; Cardiology; Medicine; Endocrinology; Phosphatase; Biology; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001882499,0.0002179202,0.000261336,0.0001773877,0.0001945842,0.0002898564,0.00009957713,0.0002674512,0.001659618],"category_scores_gemma":[0.0001721505,0.0001367103,0.0002055598,0.0001278953,0.0002473029,0.00007430759,0.000193349,0.0004314787,0.0004326822],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001299441,"about_ca_system_score_gemma":0.00009019847,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002996764,"about_ca_topic_score_gemma":0.0003248812,"domain_scores_codex":[0.9998511,0.00003395877,0.00001476998,0.00003382353,0.00002867696,0.00003753724],"domain_scores_gemma":[0.9998589,0.00002188323,0.00004957335,0.00001316785,0.00001022479,0.00004619833],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001318187,0.00008144963,0.006147707,0.00007678824,0.00002575054,0.0005668605,0.00004305927,0.00008420415,0.9885267,0.00006176785,0.000279506,0.002787947],"study_design_scores_gemma":[0.0005393119,0.003498139,0.5038118,0.00004151442,0.0002077268,0.01046489,0.0002541003,0.002979312,0.4717332,0.0002830382,0.006162464,0.00002445964],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971685,0.001316783,0.0005973084,0.0001323441,0.00003037122,0.000008464661,0.0001724378,0.00003367088,0.0005402985],"genre_scores_gemma":[0.998508,0.0004384609,0.0002656742,0.00005255102,0.00001965594,0.00001487438,0.0001533403,0.000005177872,0.0005422328],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001659618,"threshold_uncertainty_score":0.005551994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2670326179905287,"score_gpt":0.4694936554366416,"score_spread":0.2024610374461129,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}