{"id":"W4386946603","doi":"10.1021/acsomega.3c04301","title":"Synthesis and Cytotoxicity of Monomethylated Betulinic Acid 3-O-α-l-Rhamnopyranosides","year":2023,"lang":"en","type":"article","venue":"ACS Omega","topic":"Natural product bioactivities and synthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Chicoutimi","funders":"Institute of Cancer Research","keywords":"Betulinic acid; Cytotoxicity; Chemistry; Residue (chemistry); Monosaccharide; In vitro; Biochemistry; Stereochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007462949,0.0002917542,0.0001462262,0.0001297791,0.00008259776,0.0001307324,0.0001742459,0.0001395079,0.0009370873],"category_scores_gemma":[0.0000653115,0.00008170588,0.000109168,0.0001355351,0.00008577403,0.000116387,0.0000967897,0.0002591859,0.000271251],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001410126,"about_ca_system_score_gemma":0.0001068316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004396313,"about_ca_topic_score_gemma":0.000607494,"domain_scores_codex":[0.9999539,0.000007644216,0.000003889811,0.00001083773,0.00001418766,0.00000947199],"domain_scores_gemma":[0.9999564,0.000007306057,0.00001203869,0.000006098172,0.000008088147,0.00001012288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002416885,0.000003261535,0.00001235582,0.000007834918,9.190638e-7,0.00001159123,0.000003893356,0.00004654729,0.9992962,0.00002173392,0.000006439483,0.0005650685],"study_design_scores_gemma":[0.00000196983,0.00006935703,0.0003182583,0.000001344658,0.000003548999,0.00002738138,0.000003180513,0.0001057879,0.9988281,0.000009132886,0.000630547,0.00000129116],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899278,0.001246193,0.004869107,0.00004388657,0.0000152595,0.00004116806,0.0005237908,0.00009411336,0.003238705],"genre_scores_gemma":[0.9856515,0.001234342,0.007180312,0.000036094,0.000007808733,0.00005366155,0.0008442433,0.00003653639,0.004955542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009370873,"threshold_uncertainty_score":0.003134847,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0141289860186983,"score_gpt":0.2401221198487445,"score_spread":0.2259931338300462,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}