{"id":"W4386949099","doi":"10.1093/gerona/glad226","title":"The Triple Alliance: Microbiome, Mitochondria, and Metabolites in the Context of Age-Related Cognitive Decline and Alzheimer’s Disease","year":2023,"lang":"en","type":"review","venue":"The Journals of Gerontology Series A","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Dental and Craniofacial Research; Morsani College of Medicine; Institute of Aging; National Institutes of Health; Florida Department of Health; National Institute on Aging; University of South Florida; U.S. Department of Defense","keywords":"Neuroinflammation; Disease; Context (archaeology); Biology; Microbiome; Neuroscience; Aging brain; Gut flora; Cognitive decline; Population; Mediterranean diet; Inflammation; Immunology; Bioinformatics; Dementia; Medicine; Cognition; Pathology; Environmental health","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001059239,0.0006239372,0.0008621756,0.001569,0.0006572307,0.002316736,0.0004873287,0.001573775,0.005804596],"category_scores_gemma":[0.001205226,0.0001574834,0.0003828555,0.001551794,0.0008694647,0.002324583,0.002415612,0.002468121,0.001994809],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006922032,"about_ca_system_score_gemma":0.001600084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008812307,"about_ca_topic_score_gemma":0.001450179,"domain_scores_codex":[0.9996271,0.0001334104,0.00003106718,0.0000584663,0.00009091843,0.00005896545],"domain_scores_gemma":[0.9993898,0.0001584229,0.00008140678,0.00002251428,0.000153592,0.0001943748],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003667283,0.0001118732,0.002500161,0.007226733,0.0001697425,0.0006638774,0.001252749,0.0002596943,0.007043987,0.01871941,0.2130218,0.7486632],"study_design_scores_gemma":[0.00001313771,0.0001375557,0.00347955,0.002789062,0.00008447287,0.001003077,0.0005700128,0.00009895253,0.0007375919,0.009552794,0.9815038,0.00002994285],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001545743,0.9707709,0.0004452639,0.0156707,0.007960744,0.000009305956,0.00008152388,0.00004804202,0.003467737],"genre_scores_gemma":[0.01064448,0.9701751,0.0006704813,0.00369401,0.009169607,0.00001709031,0.0001165556,0.00001684455,0.005495807],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005804596,"threshold_uncertainty_score":0.0194183,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07632692296078479,"score_gpt":0.3796159343120623,"score_spread":0.3032890113512775,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}