{"id":"W4386967196","doi":"10.1002/admi.202300168","title":"Heterodimeric Protein Surface‐Coupling Platform: Immobilization of Conformation Switchable and Functional αIIbβ3 Integrin","year":2023,"lang":"en","type":"article","venue":"Advanced Materials Interfaces","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"The Scarborough Hospital; York University; Canadian Blood Services; University of Toronto; St. Michael's Hospital","funders":"Canada Foundation for Innovation; Canadian Blood Services; St. Michael's Hospital Foundation","keywords":"Integrin; Covalent bond; Biophysics; Cell adhesion; Adhesion; Ligand (biochemistry); Platelet Glycoprotein GPIIb-IIIa Complex; Materials science; Biomolecule; Nanotechnology; Chemistry; Receptor; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001031205,0.0002858723,0.0001152679,0.0001322931,0.00007912959,0.0001509832,0.0002166581,0.000334839,0.000836299],"category_scores_gemma":[0.00008167876,0.0001442073,0.000133255,0.0001042687,0.00008536832,0.0001398151,0.0002108814,0.0002405018,0.0002910694],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001308845,"about_ca_system_score_gemma":0.00009112386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002507451,"about_ca_topic_score_gemma":0.0003855816,"domain_scores_codex":[0.9999003,0.00001333796,0.000006292626,0.00002854437,0.00003231634,0.00001920392],"domain_scores_gemma":[0.9999613,0.000004875585,0.00001174281,0.000005192132,0.000006854209,0.00001004447],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000007087153,0.00000683395,0.00003168702,0.000007972047,0.000001560457,0.00001095133,0.0000036104,0.00002106194,0.9994037,0.00003943649,0.00002703081,0.0004391558],"study_design_scores_gemma":[0.0000100354,0.0001297439,0.0011982,0.000002173666,0.000007665107,0.0001120799,0.00001041523,0.001370676,0.995812,0.0000239571,0.001317786,0.000005142606],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838724,0.0006623747,0.01279446,0.00006921897,0.00004689798,0.0000348888,0.0001143427,0.0001254093,0.002280054],"genre_scores_gemma":[0.9885871,0.0003145773,0.008875715,0.00005413497,0.00001253813,0.00004030896,0.0001461607,0.00001249771,0.001956955],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000836299,"threshold_uncertainty_score":0.002797723,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03297183535860123,"score_gpt":0.301266637973984,"score_spread":0.2682948026153827,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}