{"id":"W4386967196","doi":"10.1002/admi.202300168","title":"Heterodimeric Protein Surface‐Coupling Platform: Immobilization of Conformation Switchable and Functional αIIbβ3 Integrin","year":2023,"lang":"en","type":"article","venue":"Advanced Materials Interfaces","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"The Scarborough Hospital; York University; Canadian Blood Services; University of Toronto; St. Michael's Hospital","funders":"Canada Foundation for Innovation; Canadian Blood Services; St. Michael's Hospital Foundation","keywords":"Integrin; Covalent bond; Biophysics; Cell adhesion; Adhesion; Ligand (biochemistry); Platelet Glycoprotein GPIIb-IIIa Complex; Materials science; Biomolecule; Nanotechnology; Chemistry; Receptor; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003602273,0.0001503303,0.0003119379,0.0001756755,0.00006199192,0.00002753036,0.00006064478,0.0000793806,0.0005103854],"category_scores_gemma":[0.0001718924,0.0001267226,0.00002509393,0.0002841501,0.00008756801,0.0003220741,0.0001223999,0.00009728916,0.0001321295],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004506163,"about_ca_system_score_gemma":0.00004501611,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004027985,"about_ca_topic_score_gemma":0.000003937587,"domain_scores_codex":[0.9987391,0.00002026978,0.0004657521,0.0002345406,0.0003034948,0.0002368066],"domain_scores_gemma":[0.9993232,0.00006116304,0.0001708599,0.0001899884,0.000188579,0.00006619804],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006155019,0.00002696296,0.0001503991,0.0004715053,0.00002490564,0.000002651575,0.0001547706,0.002352504,0.9945889,0.00008263926,0.00007074249,0.001458498],"study_design_scores_gemma":[0.000836745,0.000343873,0.001864327,0.000314644,0.00001257912,0.00001143282,0.0005526622,0.002498579,0.9929531,0.0001906449,0.0003132538,0.000108216],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975246,0.0001541115,0.0009441354,0.00009496805,0.0002115822,0.000760582,0.00001681008,0.0001189698,0.0001742073],"genre_scores_gemma":[0.997467,0.0002269346,0.0009841464,0.00001740874,0.00002414708,0.00005055575,0.000147068,0.00002584927,0.00105683],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001713928,"threshold_uncertainty_score":0.5588363,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03297183535860123,"score_gpt":0.301266637973984,"score_spread":0.2682948026153827,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}