{"id":"W4386968272","doi":"10.1038/s41467-023-41509-x","title":"Genotypic diversity and unrecognized antifungal resistance among populations of Candida glabrata from positive blood cultures","year":2023,"lang":"en","type":"article","venue":"Nature Communications","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Human Genome Research Institute; Center for Research Computing, University of Pittsburgh; National Institute of Allergy and Infectious Diseases; University of Pittsburgh; Division of Intramural Research, National Institute of Allergy and Infectious Diseases; U.S. Department of Veterans Affairs; York University; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Fluconazole; Biology; Candida glabrata; Genotype; Microbiology; Genetic diversity; Virulence; Drug resistance; Cryptococcus neoformans; Population; Candida albicans; Antifungal; Genetics; Medicine; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002832896,0.0002305964,0.000192662,0.0006810225,0.0003709841,0.0005824499,0.0002638155,0.0003205705,0.0008266616],"category_scores_gemma":[0.001113326,0.0001425536,0.0001507312,0.0003425051,0.0004024499,0.0001423466,0.0003817626,0.0004017806,0.0001398021],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002631324,"about_ca_system_score_gemma":0.00009793892,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001746753,"about_ca_topic_score_gemma":0.001756875,"domain_scores_codex":[0.9995357,0.000088914,0.00004403158,0.0001401598,0.00009798784,0.00009319574],"domain_scores_gemma":[0.9996377,0.00009656118,0.00007669671,0.00006368558,0.00004328086,0.00008201554],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007651309,0.0002296249,0.679614,0.00003225022,0.00007960007,0.002484792,0.001344444,0.00041388,0.2994057,0.0003077044,0.0003096348,0.01501321],"study_design_scores_gemma":[0.00004731529,0.0008272463,0.9458932,0.00001864863,0.00004952295,0.01476527,0.0009631523,0.002068979,0.03413241,0.0003151185,0.0008942797,0.0000248553],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994862,0.00004594561,0.0002002293,0.00002293925,0.000001280985,0.000004799308,0.00005535485,0.000005238161,0.0001779591],"genre_scores_gemma":[0.9995016,0.00002153668,0.0002455109,0.00002896833,0.000002862198,0.000004081503,0.0001306869,0.000002542843,0.00006229687],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001746753,"threshold_uncertainty_score":0.003473222,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03424256914694131,"score_gpt":0.3209218255214794,"score_spread":0.2866792563745381,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}