{"id":"W4386993713","doi":"10.1089/thy.2023.0255","title":"Prospective Validation of ThyroSPEC Molecular Testing of Indeterminate Thyroid Nodule Cytology Following Diagnostic Pathway Optimization","year":2023,"lang":"en","type":"article","venue":"Thyroid","topic":"Thyroid Cancer Diagnosis and Treatment","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Malignancy; Thyroid nodules; Radiology; Confidence interval; Thyroid cancer; Prospective cohort study; Nodule (geology); Indeterminate; Population; Cytology; Thyroid; Surgery; Internal medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01549032,0.0003778931,0.0004112512,0.0005898792,0.0003163163,0.001408246,0.001059059,0.0005433264,0.0007209425],"category_scores_gemma":[0.03798621,0.0002980741,0.0004488317,0.0007756419,0.0006610634,0.000598697,0.0009396676,0.0008457965,0.0003504455],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001508103,"about_ca_system_score_gemma":0.001849516,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004224048,"about_ca_topic_score_gemma":0.003844543,"domain_scores_codex":[0.9923229,0.003610162,0.0004960048,0.00150153,0.001601617,0.0004677574],"domain_scores_gemma":[0.9544761,0.02242084,0.009394927,0.004795221,0.007596071,0.001316861],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003845934,0.00009168255,0.994389,0.00001876199,0.00004516172,0.00004164339,0.0001011264,0.0006029027,0.0005602676,0.0000324972,0.00005747364,0.003674896],"study_design_scores_gemma":[0.00007459366,0.00240953,0.9759293,0.00003559101,0.0001764672,0.0004773423,0.0002482212,0.01548322,0.004365953,0.00008620136,0.0006969501,0.00001650799],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979068,0.0001374397,0.001297127,0.00005309975,0.000006455094,0.00004581909,0.0001844067,0.00002051257,0.0003484649],"genre_scores_gemma":[0.9990143,0.00002080388,0.0006920199,0.00002604404,0.00000405876,0.0000134264,0.0001840299,0.000003148546,0.00004218883],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01549032,"threshold_uncertainty_score":0.08192164,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01595500352930042,"score_gpt":0.2683246566658336,"score_spread":0.2523696531365332,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}