{"id":"W4387014301","doi":"10.1016/j.jaad.2023.07.365","title":"42262 Sustained Improvement Over 52 Weeks in Patient-Reported Itch, Symptoms, and Quality of Life With Upadacitinib in Patients With Atopic Dermatitis: Results From Phase 3 Studies (Measure Up 1, Measure Up 2, and AD Up)","year":2023,"lang":"en","type":"article","venue":"Journal of the American Academy of Dermatology","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Probity Medical Research; Queen's University","funders":"","keywords":"Medicine; Atopic dermatitis; Measure (data warehouse); Quality of life (healthcare); Dermatology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007828865,0.000531906,0.001412201,0.000239114,0.0002301235,0.0005770419,0.0003156379,0.0004338231,0.002466616],"category_scores_gemma":[0.0004173967,0.0001740721,0.001233351,0.0003060396,0.0001808718,0.0003626286,0.0002063949,0.001280101,0.0004995222],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002980894,"about_ca_system_score_gemma":0.000308247,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006995932,"about_ca_topic_score_gemma":0.002147456,"domain_scores_codex":[0.9997349,0.00008721488,0.00001970311,0.00003888212,0.00005373266,0.00006552582],"domain_scores_gemma":[0.9997986,0.00004070554,0.00005467211,0.00001841307,0.00003147043,0.00005613428],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.283829,0.02875143,0.02615034,0.002805111,0.004776081,0.0005976809,0.0002301226,0.002258097,0.09024573,0.0001607849,0.00976853,0.5504271],"study_design_scores_gemma":[0.2553416,0.3754665,0.3240542,0.0003855726,0.003754641,0.001981608,0.0002497472,0.003526757,0.02532193,0.0002277613,0.009548047,0.0001415114],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895517,0.006540365,0.0002369351,0.0002126227,0.00007770487,0.0003100601,0.000809369,0.0001226373,0.002138517],"genre_scores_gemma":[0.9941088,0.002209064,0.0005019075,0.0003171708,0.00005952318,0.0002205082,0.001269518,0.00001295395,0.001300657],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002466616,"threshold_uncertainty_score":0.008251667,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02616315145235814,"score_gpt":0.3228975051290781,"score_spread":0.29673435367672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}