{"id":"W4387022366","doi":"10.26434/chemrxiv-2023-82ztv","title":"Liver-Type Fatty Acid Binding Protein (FABP1) Has Exceptional Affinity for Minor Cannabinoids","year":2023,"lang":"en","type":"preprint","venue":"ChemRxiv","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Windsor","funders":"Natural Sciences and Engineering Research Council of Canada; Compute Canada","keywords":"Fatty acid-binding protein; Fatty acid; Nonalcoholic fatty liver disease; Biochemistry; Binding affinities; Transporter; In silico; Chemistry; Biology; Fatty liver; Gene; Disease; Receptor; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001262812,0.000577884,0.000654901,0.0002127684,0.000443393,0.0004598987,0.0003729097,0.0007792105,0.00307784],"category_scores_gemma":[0.0004378364,0.0001925048,0.0004750288,0.0003016091,0.000275365,0.0002887485,0.0002857832,0.0004572207,0.0009400719],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004991852,"about_ca_system_score_gemma":0.0004648489,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007760264,"about_ca_topic_score_gemma":0.006055108,"domain_scores_codex":[0.9999052,0.00001521917,0.000003070331,0.00003076452,0.0000224346,0.00002329644],"domain_scores_gemma":[0.9999045,0.00004170297,0.00001553926,0.000006689084,0.00001544761,0.00001608605],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001187312,0.0002360562,0.02274639,0.00108136,0.0002427545,0.0009723884,0.0001337752,0.4968766,0.4275668,0.008255022,0.004726232,0.03597538],"study_design_scores_gemma":[0.00008853019,0.0003299041,0.007449972,0.00004138916,0.0001192327,0.0004653409,0.0001062804,0.8696488,0.106292,0.006274672,0.009132311,0.00005159878],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9500353,0.003024101,0.03751587,0.0007720664,0.00007134759,0.00002478645,0.001404238,0.0005141624,0.006638193],"genre_scores_gemma":[0.9834983,0.001177597,0.01012087,0.0001086254,0.00001289953,0.00002316852,0.001697113,0.00006460724,0.003296882],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007760264,"threshold_uncertainty_score":0.01543015,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1030246175626157,"score_gpt":0.3346545711945908,"score_spread":0.2316299536319751,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}