{"id":"W4387026377","doi":"10.1016/j.jaad.2023.07.714","title":"42065 Improvement in Itch, Symptoms, and Quality of Life With Upadacitinib Through Week 16 in Adults and Adolescents With Atopic Dermatitis: Results From Phase 3 Studies (Measure Up 1, Measure Up 2, and AD Up)","year":2023,"lang":"en","type":"article","venue":"Journal of the American Academy of Dermatology","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Ortho Dermatologics","keywords":"Medicine; Placebo; Atopic dermatitis; Post-hoc analysis; Quality of life (healthcare); Internal medicine; Anesthesia; Dermatology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001483903,0.0004764588,0.001549275,0.0003244718,0.0002686677,0.0005451989,0.0003367922,0.0005405968,0.001736457],"category_scores_gemma":[0.0008571159,0.0002491501,0.001785979,0.0004096161,0.0002818615,0.0005835813,0.0002693556,0.001429973,0.000263088],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003847422,"about_ca_system_score_gemma":0.0004853593,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001441154,"about_ca_topic_score_gemma":0.004399432,"domain_scores_codex":[0.9995742,0.0001814848,0.00003611462,0.00005097998,0.00007215677,0.00008491474],"domain_scores_gemma":[0.9995629,0.00008947556,0.0001414015,0.00003059428,0.0000603542,0.0001151465],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.5475066,0.03834694,0.06765012,0.0028506,0.009091047,0.0001998744,0.0004521743,0.001304899,0.01950145,0.0001446776,0.00417814,0.3087734],"study_design_scores_gemma":[0.2102457,0.390615,0.386531,0.0003509458,0.004277787,0.0003079782,0.000244537,0.0009286266,0.003393916,0.0001007749,0.00294069,0.00006309206],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944878,0.00386026,0.00009695632,0.0001000285,0.00004167002,0.0002923271,0.000474213,0.00003159937,0.0006151606],"genre_scores_gemma":[0.9956124,0.002093327,0.0003756878,0.0002310137,0.00004247369,0.0003044514,0.0006998967,0.000006308367,0.0006345136],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001736457,"threshold_uncertainty_score":0.007847726,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03957076075616715,"score_gpt":0.3387112788749022,"score_spread":0.299140518118735,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}