{"id":"W4387077012","doi":"10.1080/14737159.2023.2264181","title":"Retrospective analysis of persistent HyperCKemia with or without muscle weakness in a case series from Greece highlights vast <i>DMD</i> variant heterogeneity","year":2023,"lang":"en","type":"article","venue":"Expert Review of Molecular Diagnostics","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; Children's Hospital of Eastern Ontario; University of Ottawa","funders":"","keywords":"Weakness; Medicine; Muscle weakness; Internal medicine; Anatomy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000201827,0.0002694175,0.0008247585,0.00012928,0.00005026312,0.000006273066,0.00022847,0.0001483,0.000036596],"category_scores_gemma":[0.0004186621,0.0002055924,0.0004059852,0.0009328034,0.0001989675,0.00000870253,0.0001511459,0.00009501736,0.000002514533],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002478265,"about_ca_system_score_gemma":0.0001048978,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004429203,"about_ca_topic_score_gemma":0.001180717,"domain_scores_codex":[0.9982866,0.0002194569,0.0004701908,0.0005389703,0.0002238019,0.0002609986],"domain_scores_gemma":[0.998711,0.00006806816,0.0002308675,0.0007070132,0.0001940862,0.00008899831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002507034,0.002635975,0.1111668,0.005306331,0.01686777,0.0100019,0.002804969,0.004461044,0.8325466,0.0006061894,0.004937862,0.006157458],"study_design_scores_gemma":[0.01180166,0.01196288,0.2227345,0.01683219,0.0172078,0.001517612,0.004492289,0.003341358,0.6714341,0.0002470509,0.03260287,0.005825702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9670159,0.03153881,0.0004585637,0.0002301193,0.00007134097,0.0004093797,0.0001860129,0.00001426513,0.00007561549],"genre_scores_gemma":[0.9112526,0.08679432,0.0008296474,0.0004875722,0.00003144172,0.00009939351,0.0004644982,0.00002735557,0.00001313434],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1611125,"threshold_uncertainty_score":0.8383814,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01144847359915905,"score_gpt":0.2775931018722398,"score_spread":0.2661446282730808,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}