{"id":"W4387081589","doi":"10.1093/clinchem/hvad097.402","title":"B-062 A Self-Imposed Gray Area? Analysis of Anti-Tissue Transglutaminase and Anti-Endomysial Antibody Discordance in a Celiac Disease Screening Serology Testing Algorithm","year":2023,"lang":"en","type":"article","venue":"Clinical Chemistry","topic":"Celiac Disease Research and Management","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary Laboratory Services; University of Calgary","funders":"","keywords":"Serology; Tissue transglutaminase; Concordance; Medicine; Immunology; Asymptomatic; Antibody; Population; Immunoglobulin A; Internal medicine; Immunoglobulin G; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008951516,0.0002596849,0.001074711,0.0002593618,0.00006412983,0.00002566159,0.0001821114,0.0001341627,0.0000518953],"category_scores_gemma":[0.001151626,0.0002410173,0.0003322726,0.001842583,0.0003199337,0.00007345989,0.000197823,0.0004241487,0.000005088167],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002745029,"about_ca_system_score_gemma":0.0001807663,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004736946,"about_ca_topic_score_gemma":0.000004669902,"domain_scores_codex":[0.9971892,0.0001071786,0.0008966022,0.0007719529,0.0004376261,0.0005974974],"domain_scores_gemma":[0.9976596,0.0007668458,0.0001812371,0.0005263016,0.0001028046,0.0007632712],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004564501,0.001088962,0.9361163,0.001258826,0.001060187,0.00283785,0.00004484313,0.0001588994,0.0313647,0.000002289149,0.000120836,0.0254899],"study_design_scores_gemma":[0.004838037,0.0001495112,0.8890936,0.0003080016,0.002307983,0.000008130098,0.0001871533,0.0997178,0.002654447,0.00002341273,0.0004274671,0.0002844718],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997106,0.0004462048,0.0009946715,0.0005778929,0.00003698068,0.000418963,0.0001802722,0.0001316613,0.0001074218],"genre_scores_gemma":[0.996166,0.001099625,0.00172509,0.0000886499,0.0001495583,0.00003688897,0.0005838645,0.00002868602,0.0001216191],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0995589,"threshold_uncertainty_score":0.9828401,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04903419358368143,"score_gpt":0.3959564445703887,"score_spread":0.3469222509867073,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}